STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Herpud1annotation not available (179 aa)    
Predicted Functional Partners:
Syvn1
E3 ubiquitin-protein ligase synoviolin.
    
 
 0.826
Amfr
E3 ubiquitin-protein ligase AMFR.
    
 
 0.812
Atf4
Cyclic AMP-dependent transcription factor ATF-4.
   
 
 0.693
Atf5
Cyclic AMP-dependent transcription factor ATF-5.
     
 0.571
Zfp622
Zinc finger protein 622.
      
 0.567
Manf
Mesencephalic astrocyte-derived neurotrophic factor.
      
 0.549
Sel1l
Protein sel-1 homolog 1; Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling. Belongs to the sel-1 family.
    
 
 0.497
Rnf145
RING finger protein 145 isoform X1.
    
 
 0.482
Vcp
Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.
    
 
 0.479
Cth
Cystathionine gamma-lyase isoform X2.
      
 0.479
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.