STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Megf8Multiple epidermal growth factor-like domains protein 8. (2789 aa)    
Predicted Functional Partners:
Smo
Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.866
Mgrn1
E3 ubiquitin-protein ligase MGRN1 isoform X7.
   
 
 0.856
Pafah1b1
Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]
    
 0.732
Tbc1d31
TBC1 domain family member 31 isoform X2.
    
 0.732
Rnf157
RING finger protein 157 isoform X1.
   
 
 0.654
Mboat2
Lysophospholipid acyltransferase 2 isoform X1; Belongs to the membrane-bound acyltransferase family.
   
 
  0.586
Mosmo
Uncharacterized protein C16orf52 homolog.
      
 0.568
Cul7
Cullin-7 isoform X2; Belongs to the cullin family.
   
   0.465
Card19
Caspase recruitment domain-containing protein 19 isoform X1.
      
 0.455
Abtb1
Ankyrin repeat and BTB/POZ domain-containing protein 1 isoform X1.
    
 
 0.436
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.