STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SykTyrosine-protein kinase. (629 aa)    
Predicted Functional Partners:
Cd3e
T-cell surface glycoprotein CD3 epsilon chain.
   
 0.997
Vav1
Proto-oncogene vav.
   
 0.997
Fcer1g
High affinity immunoglobulin epsilon receptor subunit gamma.
   
 0.996
Plcg1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
0.994
Tyrobp
TYRO protein tyrosine kinase-binding protein.
   
 0.993
Cbl
E3 ubiquitin-protein ligase CBL.
    
 0.993
Plcg2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
   
0.986
ENSMAUP00000008458
annotation not available
   
 0.978
Cd247
LOW QUALITY PROTEIN: T-cell surface glycoprotein CD3 zeta chain.
   
 0.978
Vav3
Guanine nucleotide exchange factor VAV3 isoform X1.
   
 0.976
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.