STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kctd15BTB/POZ domain-containing protein KCTD15. (288 aa)    
Predicted Functional Partners:
Ube2i
SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451 (By similarity). Can catalyze the formation of poly-SUMO chains (By similarity). Essential for nuclear architecture and chromosome segregation (By similarity). Necessary for sumoylation of FOXL2 and KAT5 (By similarity). Sumoylates p53/TP53 at 'Lys-386' (By similarity). Mediates sumoylation of ERCC6 which is essential for its transcription-coupled [...]
    
 
 0.941
Tfap2c
LOW QUALITY PROTEIN: transcription factor AP-2 gamma.
    
 0.800
Tfap2d
Transcription factor AP-2-delta isoform X2.
    
 0.797
Tfap2a
Transcription factor AP-2-alpha.
    
 0.784
Tfap2b
Transcription factor AP-2-beta.
    
 0.756
Tfap2e
Transcription factor AP-2-epsilon.
    
 0.756
Cul3
Cullin-3; Belongs to the cullin family.
    
 0.644
Kiaa1958
Uncharacterized protein KIAA1958 homolog.
    
 0.622
Cul1
Cullin-1; Belongs to the cullin family.
    
 0.612
Cacul1
CDK2-associated and cullin domain-containing protein 1 isoform X1; Belongs to the cullin family.
    
 0.581
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.