node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Alyref | Cdc40 | ENSMAUP00000023396 | ENSMAUP00000021265 | THO complex subunit 4. | pre-mRNA-processing factor 17. | 0.975 |
Alyref | Ncbp1 | ENSMAUP00000023396 | ENSMAUP00000023447 | THO complex subunit 4. | Nuclear cap-binding protein subunit 1. | 0.993 |
Alyref | Ncbp2 | ENSMAUP00000023396 | ENSMAUP00000024716 | THO complex subunit 4. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.995 |
Alyref | Nelfe | ENSMAUP00000023396 | ENSMAUP00000018144 | THO complex subunit 4. | Negative elongation factor E isoform X2. | 0.544 |
Alyref | Slbp | ENSMAUP00000023396 | ENSMAUP00000007955 | THO complex subunit 4. | Histone RNA hairpin-binding protein isoform X1. | 0.977 |
Alyref | Snrpd2 | ENSMAUP00000023396 | ENSMAUP00000020980 | THO complex subunit 4. | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. | 0.712 |
Alyref | Snrpd3 | ENSMAUP00000023396 | ENSMAUP00000024574 | THO complex subunit 4. | Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. | 0.925 |
Alyref | Snrpe | ENSMAUP00000023396 | ENSMAUP00000001093 | THO complex subunit 4. | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. | 0.911 |
Alyref | Snrpg | ENSMAUP00000023396 | ENSMAUP00000023355 | THO complex subunit 4. | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. | 0.882 |
Alyref | Srrt | ENSMAUP00000023396 | ENSMAUP00000010526 | THO complex subunit 4. | Serrate RNA effector molecule homolog isoform X1. | 0.991 |
Cdc40 | Alyref | ENSMAUP00000021265 | ENSMAUP00000023396 | pre-mRNA-processing factor 17. | THO complex subunit 4. | 0.975 |
Cdc40 | Ncbp1 | ENSMAUP00000021265 | ENSMAUP00000023447 | pre-mRNA-processing factor 17. | Nuclear cap-binding protein subunit 1. | 0.994 |
Cdc40 | Ncbp2 | ENSMAUP00000021265 | ENSMAUP00000024716 | pre-mRNA-processing factor 17. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.995 |
Cdc40 | Nelfe | ENSMAUP00000021265 | ENSMAUP00000018144 | pre-mRNA-processing factor 17. | Negative elongation factor E isoform X2. | 0.497 |
Cdc40 | Snrpd2 | ENSMAUP00000021265 | ENSMAUP00000020980 | pre-mRNA-processing factor 17. | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. | 0.993 |
Cdc40 | Snrpd3 | ENSMAUP00000021265 | ENSMAUP00000024574 | pre-mRNA-processing factor 17. | Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. | 0.995 |
Cdc40 | Snrpe | ENSMAUP00000021265 | ENSMAUP00000001093 | pre-mRNA-processing factor 17. | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. | 0.992 |
Cdc40 | Snrpg | ENSMAUP00000021265 | ENSMAUP00000023355 | pre-mRNA-processing factor 17. | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. | 0.995 |
Ncbp1 | Alyref | ENSMAUP00000023447 | ENSMAUP00000023396 | Nuclear cap-binding protein subunit 1. | THO complex subunit 4. | 0.993 |
Ncbp1 | Cdc40 | ENSMAUP00000023447 | ENSMAUP00000021265 | Nuclear cap-binding protein subunit 1. | pre-mRNA-processing factor 17. | 0.994 |