STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sp110Sp110 nuclear body protein. (339 aa)    
Predicted Functional Partners:
Ddx58
Putative ATP-dependent RNA helicase DDX58.
   
 0.826
Parp9
Poly (ADP-ribose) polymerase family, member 9.
   
   0.780
Ifi35
Interferon-induced 35 kDa protein isoform X1.
   
  
 0.753
Ube2i
SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451 (By similarity). Can catalyze the formation of poly-SUMO chains (By similarity). Essential for nuclear architecture and chromosome segregation (By similarity). Necessary for sumoylation of FOXL2 and KAT5 (By similarity). Sumoylates p53/TP53 at 'Lys-386' (By similarity). Mediates sumoylation of ERCC6 which is essential for its transcription-coupled [...]
    
 0.707
Zfand4
AN1-type zinc finger protein 4 isoform X2.
    
 0.662
Stat1
Signal transducer and activator of transcription.
   
  0.629
Ube2l3
Ubiquitin-conjugating enzyme E2 L3 isoform X1; Belongs to the ubiquitin-conjugating enzyme family.
   
  0.627
Rps27a
ubiquitin-40S ribosomal protein S27a.
    
  0.617
Isg15
Ubiquitin-like protein ISG15.
   
 0.617
ENSMAUP00000019431
annotation not available
    
  0.617
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.