node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aasdh | Cyb5r4 | ENSMAUP00000008104 | ENSMAUP00000021440 | acyl-CoA synthetase family member 4 isoform X1. | Cytochrome b5 reductase 4 isoform X1. | 0.517 |
Aasdh | Cyp17a1 | ENSMAUP00000008104 | ENSMAUP00000015990 | acyl-CoA synthetase family member 4 isoform X1. | Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] | 0.798 |
Aasdh | Cyp26b1 | ENSMAUP00000008104 | ENSMAUP00000002110 | acyl-CoA synthetase family member 4 isoform X1. | Cytochrome P450 26B1; Belongs to the cytochrome P450 family. | 0.823 |
Aasdh | Cyp7a1 | ENSMAUP00000008104 | ENSMAUP00000011088 | acyl-CoA synthetase family member 4 isoform X1. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.797 |
Aasdh | ENSMAUP00000000801 | ENSMAUP00000008104 | ENSMAUP00000000801 | acyl-CoA synthetase family member 4 isoform X1. | annotation not available | 0.993 |
Aasdh | Ephx2 | ENSMAUP00000008104 | ENSMAUP00000009666 | acyl-CoA synthetase family member 4 isoform X1. | Bifunctional epoxide hydrolase 2. | 0.843 |
Aasdh | LOC101830378 | ENSMAUP00000008104 | ENSMAUP00000024206 | acyl-CoA synthetase family member 4 isoform X1. | Cytochrome P450 2C26-like isoform X2; Belongs to the cytochrome P450 family. | 0.798 |
Aasdh | LOC101836914 | ENSMAUP00000008104 | ENSMAUP00000013162 | acyl-CoA synthetase family member 4 isoform X1. | Cytochrome P450 3A31; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.824 |
Aasdh | Lss | ENSMAUP00000008104 | ENSMAUP00000004363 | acyl-CoA synthetase family member 4 isoform X1. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.607 |
Aasdh | Suox | ENSMAUP00000008104 | ENSMAUP00000012162 | acyl-CoA synthetase family member 4 isoform X1. | Sulfite oxidase, mitochondrial. | 0.607 |
Cyb5r4 | Aasdh | ENSMAUP00000021440 | ENSMAUP00000008104 | Cytochrome b5 reductase 4 isoform X1. | acyl-CoA synthetase family member 4 isoform X1. | 0.517 |
Cyb5r4 | Cyp17a1 | ENSMAUP00000021440 | ENSMAUP00000015990 | Cytochrome b5 reductase 4 isoform X1. | Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] | 0.724 |
Cyb5r4 | Cyp26b1 | ENSMAUP00000021440 | ENSMAUP00000002110 | Cytochrome b5 reductase 4 isoform X1. | Cytochrome P450 26B1; Belongs to the cytochrome P450 family. | 0.860 |
Cyb5r4 | Cyp7a1 | ENSMAUP00000021440 | ENSMAUP00000011088 | Cytochrome b5 reductase 4 isoform X1. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.756 |
Cyb5r4 | ENSMAUP00000000801 | ENSMAUP00000021440 | ENSMAUP00000000801 | Cytochrome b5 reductase 4 isoform X1. | annotation not available | 0.411 |
Cyb5r4 | Ephx2 | ENSMAUP00000021440 | ENSMAUP00000009666 | Cytochrome b5 reductase 4 isoform X1. | Bifunctional epoxide hydrolase 2. | 0.791 |
Cyb5r4 | LOC101830378 | ENSMAUP00000021440 | ENSMAUP00000024206 | Cytochrome b5 reductase 4 isoform X1. | Cytochrome P450 2C26-like isoform X2; Belongs to the cytochrome P450 family. | 0.724 |
Cyb5r4 | LOC101836914 | ENSMAUP00000021440 | ENSMAUP00000013162 | Cytochrome b5 reductase 4 isoform X1. | Cytochrome P450 3A31; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.792 |
Cyb5r4 | Lss | ENSMAUP00000021440 | ENSMAUP00000004363 | Cytochrome b5 reductase 4 isoform X1. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.597 |
Cyb5r4 | Suox | ENSMAUP00000021440 | ENSMAUP00000012162 | Cytochrome b5 reductase 4 isoform X1. | Sulfite oxidase, mitochondrial. | 0.946 |