STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFW78177.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (472 aa)    
Predicted Functional Partners:
SFW67853.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
   
 0.921
SFW87119.1
Ketoacyl-synthetase C-terminal extension.
  
 0.865
SFW61458.1
Amino acid adenylation domain-containing protein.
  
 0.851
SFW42118.1
Glutamate synthase (NADPH/NADH) large chain.
  
 
 0.832
SFW81012.1
Allosteric NADP-dependent malic enzyme.
  
 
 0.722
SFW71480.1
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
   
 0.692
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
 
 0.689
SFW70406.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.679
fumC
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.650
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.628
Your Current Organism:
Chitinophaga sancti
NCBI taxonomy Id: 1004
Other names: ATCC 23092, C. sancti, DSM 784, Flexibacter sancti, Flexibacter santosii, IFO 15057, LMG 8377, LMG:8377, NBRC 15057
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