STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
putAMultifunctional: transcriptional repressor of proline utilization; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1207 aa)    
Predicted Functional Partners:
CFU_1092
Hypothetical protein.
  
  
 0.970
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.956
gdhA
NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.948
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
    
 0.945
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.943
gltB
Glutamate synthase [NADPH] large chain.
  
 
 0.942
CFU_3543
Ornithine cyclodeaminase.
  
 
 0.942
gdh2
NAD-specific glutamate dehydrogenase, large form.
  
  
 0.933
rocD
Ornithine aminotransferase (Ornithine--oxo-acid aminotransferase); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.927
CFU_4197
D-alanine aminotransferase.
   
 0.925
Your Current Organism:
Collimonas fungivorans
NCBI taxonomy Id: 1005048
Other names: C. fungivorans Ter331, Collimonas fungivorans Ter331, Collimonas fungivorans str. Ter331, Collimonas fungivorans strain Ter331, beta proteobacterium Ter331
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.