node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dnaK | gmk | GBAG_3512 | GBAG_4225 | DnaK family chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.401 |
dnaK | tatD | GBAG_3512 | GBAG_0011 | DnaK family chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | TatD family deoxyribonuclease; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily. | 0.433 |
gmk | dnaK | GBAG_4225 | GBAG_3512 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DnaK family chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.401 |
gmk | metG | GBAG_4225 | GBAG_2738 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.579 |
gmk | tatD | GBAG_4225 | GBAG_0011 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | TatD family deoxyribonuclease; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily. | 0.432 |
hemB | tatA | GBAG_0010 | GBAG_0014 | Protein involved in porphobilinogen synthase activity, metal ion binding, heme biosynthetic process and tetrapyrrole biosynthetic process; Belongs to the ALAD family. | TatA family twin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.615 |
hemB | tatB | GBAG_0010 | GBAG_0013 | Protein involved in porphobilinogen synthase activity, metal ion binding, heme biosynthetic process and tetrapyrrole biosynthetic process; Belongs to the ALAD family. | TatB family twin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.617 |
hemB | tatC | GBAG_0010 | GBAG_0012 | Protein involved in porphobilinogen synthase activity, metal ion binding, heme biosynthetic process and tetrapyrrole biosynthetic process; Belongs to the ALAD family. | TatC family twin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.661 |
hemB | tatD | GBAG_0010 | GBAG_0011 | Protein involved in porphobilinogen synthase activity, metal ion binding, heme biosynthetic process and tetrapyrrole biosynthetic process; Belongs to the ALAD family. | TatD family deoxyribonuclease; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily. | 0.767 |
hemB | ubiB | GBAG_0010 | GBAG_0015 | Protein involved in porphobilinogen synthase activity, metal ion binding, heme biosynthetic process and tetrapyrrole biosynthetic process; Belongs to the ALAD family. | Ubiquinone biosynthesis monooxygenase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.515 |
hemB | ubiE | GBAG_0010 | GBAG_0017 | Protein involved in porphobilinogen synthase activity, metal ion binding, heme biosynthetic process and tetrapyrrole biosynthetic process; Belongs to the ALAD family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.512 |
hemB | yigP | GBAG_0010 | GBAG_0016 | Protein involved in porphobilinogen synthase activity, metal ion binding, heme biosynthetic process and tetrapyrrole biosynthetic process; Belongs to the ALAD family. | YigP family protein; COG3165; Protein involved in sterol binding and biological_process. | 0.468 |
metG | gmk | GBAG_2738 | GBAG_4225 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.579 |
metG | tatD | GBAG_2738 | GBAG_0011 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | TatD family deoxyribonuclease; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily. | 0.443 |
tatA | hemB | GBAG_0014 | GBAG_0010 | TatA family twin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Protein involved in porphobilinogen synthase activity, metal ion binding, heme biosynthetic process and tetrapyrrole biosynthetic process; Belongs to the ALAD family. | 0.615 |
tatA | tatB | GBAG_0014 | GBAG_0013 | TatA family twin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | TatB family twin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.994 |
tatA | tatC | GBAG_0014 | GBAG_0012 | TatA family twin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | TatC family twin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.992 |
tatA | tatD | GBAG_0014 | GBAG_0011 | TatA family twin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | TatD family deoxyribonuclease; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily. | 0.654 |
tatA | ubiB | GBAG_0014 | GBAG_0015 | TatA family twin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Ubiquinone biosynthesis monooxygenase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.642 |
tatA | ubiE | GBAG_0014 | GBAG_0017 | TatA family twin-arginine translocation protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.626 |