STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ushAUDP-sugar hydrolase/5'-nucleotidase; Protein involved in hydrolase activity and nucleotide catabolic process; Belongs to the 5'-nucleotidase family. (550 aa)    
Predicted Functional Partners:
udk
Uridine kinase; Protein involved in ATP binding, kinase activity, uridine kinase activity, phosphotransferase activity, alcohol group as acceptor, uridine metabolic process and metabolic process.
 
 
 0.943
tdk
Protein involved in thymidine kinase activity and ATP binding.
 
  
  0.934
cpdB
Protein involved in hydrolase activity, 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity, nucleobase-containing compound metabolic process, nucleotide catabolic process and nucleotide metabolic process; Belongs to the 5'-nucleotidase family.
 
 
0.931
add
Protein involved in deaminase activity, purine-containing compound salvage and purine ribonucleoside monophosphate biosynthetic process; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
  
 0.928
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
 
  
 0.927
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.920
surE
SurE family 5'-nucleotidase; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
     
 0.919
nadR
HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes; Protein involved in sequence-specific DNA binding, DNA binding, catalytic activity, transport, pyridine nucleotide biosynthetic process, (DEPRECATED) transcription, regulation of transcription, DNA-templated and biosynthetic process.
     
 0.919
deoD
Protein involved in catalytic activity, purine-nucleoside phosphorylase activity, purine nucleobase salvage, nucleoside metabolic process and nucleobase-containing compound metabolic process.
 
 
  0.918
xapA
Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.917
Your Current Organism:
Buttiauxella agrestis
NCBI taxonomy Id: 1006004
Other names: B. agrestis ATCC 33320, Buttiauxella agrestis ATCC 33320, Buttiauxella agrestis CDC 11786-81, Buttiauxella agrestis CIP 80.31, Buttiauxella agrestis CUETM 77-167, Buttiauxella agrestis DSM 4586, Buttiauxella agrestis str. ATCC 33320, Buttiauxella agrestis strain ATCC 33320
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