STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CopAHeavy metal transporting ATPase; Protein involved in nucleotide binding, metal ion binding, cation-transporting ATPase activity, copper ion transport, metal ion transport and cation transport. (835 aa)    
Predicted Functional Partners:
sodC
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.990
CadA
Heavy metal transporting ATPase; Protein involved in nucleotide binding, metal ion binding, cation-transporting ATPase activity, cadmium ion transport and cation transport.
 
 
0.868
ZntA
Heavy metal transporting ATPase; Protein involved in metal ion binding, nucleotide binding, cation-transporting ATPase activity, copper ion transport, metal ion transport and cation transport.
 
 
0.864
frmR
YaiN family protein; Protein involved in (DEPRECATED) transcription and (DEPRECATED) regulation of transcription.
  
  
 0.722
cueO
Blue copper oxidase; Protein involved in oxidoreductase activity, copper ion binding, response to copper ion and oxidation-reduction process.
 
 
 0.714
sufI
Putative cell division protein; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress; Belongs to the FtsP family.
 
 
 0.704
dps
DNA-binding ferritin-like protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction; Belongs to the Dps family.
  
  
 0.676
cueR
CueR family HTH-type transcriptional regulator; Protein involved in DNA binding, sequence-specific DNA binding transcription factor activity, copper ion binding, nucleotide binding, regulation of transcription, DNA-templated, cellular copper ion homeostasis, response to copper ion and positive regulation of transcription, DNA-templated.
  
  
 0.655
GBAG_2173
Arsenical resistance operon repressor; A single nucleotide substitution within codon 186 relative to Leclercia adecarboxylata ATCC 23216 (ASAP:AME-0002836) results in a termination codon; ArsH family arsenic resistance protein (pseudogene).
 
  
 0.652
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
  
 
 0.612
Your Current Organism:
Buttiauxella agrestis
NCBI taxonomy Id: 1006004
Other names: B. agrestis ATCC 33320, Buttiauxella agrestis ATCC 33320, Buttiauxella agrestis CDC 11786-81, Buttiauxella agrestis CIP 80.31, Buttiauxella agrestis CUETM 77-167, Buttiauxella agrestis DSM 4586, Buttiauxella agrestis str. ATCC 33320, Buttiauxella agrestis strain ATCC 33320
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