node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GBAG_1065 | GBAG_2574 | GBAG_1065 | GBAG_2574 | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | Threonine kinase; Protein involved in ATP binding. | 0.966 |
GBAG_1065 | cbiA | GBAG_1065 | GBAG_2573 | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.977 |
GBAG_1065 | cbiB | GBAG_1065 | GBAG_2572 | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.984 |
GBAG_1065 | cbiC | GBAG_1065 | GBAG_2571 | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | Protein involved in precorrin-8X methylmutase activity and cobalamin biosynthetic process. | 0.897 |
GBAG_1065 | cbiP | GBAG_1065 | GBAG_2557 | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.975 |
GBAG_1065 | hisB | GBAG_1065 | GBAG_2587 | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | Protein involved in imidazoleglycerol-phosphate dehydratase activity, phosphatase activity, histidinol-phosphatase activity and histidine biosynthetic process. | 0.971 |
GBAG_1065 | hisE | GBAG_1065 | GBAG_2591 | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Protein involved in phosphoribosyl-AMP cyclohydrolase activity, phosphoribosyl-ATP diphosphatase activity and histidine biosynthetic process; In the N-terminal section; belongs to the PRA-CH family. | 0.966 |
GBAG_1065 | hisF | GBAG_1065 | GBAG_2590 | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | Imidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.838 |
GBAG_1065 | hisH | GBAG_1065 | GBAG_2588 | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | Imidazole glycerol phosphate synthase amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.848 |
GBAG_1065 | tyrA | GBAG_1065 | GBAG_3141 | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | Chorismate mutase I/cyclohexadienyl dehydrogenase; Protein involved in prephenate dehydrogenase (NADP+) activity, prephenate dehydrogenase activity, chorismate mutase activity, L-phenylalanine biosynthetic process, tyrosine biosynthetic process, oxidation-reduction process and chorismate metabolic process. | 0.865 |
GBAG_2574 | GBAG_1065 | GBAG_2574 | GBAG_1065 | Threonine kinase; Protein involved in ATP binding. | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | 0.966 |
GBAG_2574 | cbiA | GBAG_2574 | GBAG_2573 | Threonine kinase; Protein involved in ATP binding. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.507 |
GBAG_2574 | cbiC | GBAG_2574 | GBAG_2571 | Threonine kinase; Protein involved in ATP binding. | Protein involved in precorrin-8X methylmutase activity and cobalamin biosynthetic process. | 0.568 |
GBAG_2574 | cbiP | GBAG_2574 | GBAG_2557 | Threonine kinase; Protein involved in ATP binding. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.503 |
cbiA | GBAG_1065 | GBAG_2573 | GBAG_1065 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | 0.977 |
cbiA | GBAG_2574 | GBAG_2573 | GBAG_2574 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Threonine kinase; Protein involved in ATP binding. | 0.507 |
cbiA | cbiB | GBAG_2573 | GBAG_2572 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.978 |
cbiA | cbiC | GBAG_2573 | GBAG_2571 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Protein involved in precorrin-8X methylmutase activity and cobalamin biosynthetic process. | 0.998 |
cbiA | cbiP | GBAG_2573 | GBAG_2557 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.978 |
cbiB | GBAG_1065 | GBAG_2572 | GBAG_1065 | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | L-threonine 3-O-phosphate decarboxylase; Protein involved in pyridoxal phosphate binding, catalytic activity, cobalamin biosynthetic process and biosynthetic process. | 0.984 |