STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (217 aa)    
Predicted Functional Partners:
ygaD
Putative DNA repair protein; Belongs to the CinA family.
 
 
 0.961
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
 
 
 0.950
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
  
 
 0.942
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.942
nadC
Quinolinate phosphoribosyltransferase; Protein involved in nicotinate-nucleotide diphosphorylase (carboxylating) activity, transferase activity, transferring pentosyl groups, pyridine nucleotide biosynthetic process and NAD biosynthetic process; Belongs to the NadC/ModD family.
    
 0.940
nadR
HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes; Protein involved in sequence-specific DNA binding, DNA binding, catalytic activity, transport, pyridine nucleotide biosynthetic process, (DEPRECATED) transcription, regulation of transcription, DNA-templated and biosynthetic process.
     
 0.939
cobB
SIR2 family NAD-dependent protein deacetylase; Protein involved in NAD+ binding, chromatin silencing, chemotaxis and protein deacetylation; Belongs to the sirtuin family. Class III subfamily.
   
 0.938
yjjG
5'-nucleotidase; Protein involved in hydrolase activity, thymine metabolic process, pyrimidine nucleobase salvage, response to xenobiotic stimulus and metabolic process.
    
 0.910
GBAG_3841
Putative hydrolase; FIG001957; Protein involved in hydrolase activity and metabolic process.
    
 0.910
pntA
NAD(P) transhydrogenase alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.
     
 0.909
Your Current Organism:
Buttiauxella agrestis
NCBI taxonomy Id: 1006004
Other names: B. agrestis ATCC 33320, Buttiauxella agrestis ATCC 33320, Buttiauxella agrestis CDC 11786-81, Buttiauxella agrestis CIP 80.31, Buttiauxella agrestis CUETM 77-167, Buttiauxella agrestis DSM 4586, Buttiauxella agrestis str. ATCC 33320, Buttiauxella agrestis strain ATCC 33320
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.