STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
nagKGlucokinase; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. (303 aa)    
Predicted Functional Partners:
nanE
N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
 
 0.935
nagA
Protein involved in hydrolase activity, N-acetylglucosamine-6-phosphate deacetylase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, amino sugar metabolic process and N-acetylglucosamine metabolic process.
 
 
 0.926
nagE
PTS system N-acetylglucosamine-specific IIABC components; Protein involved in sugar:hydrogen symporter activity, protein-N(PI)-phosphohistidine-sugar phosphotransferase activity, N-acetylglucosamine transmembrane transporter activity, transport and phosphoenolpyruvate-dependent sugar phosphotransferase system.
   
 0.922
GBAG_3620
Beta-hexosaminidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds and carbohydrate metabolic process.
 
 
 0.918
murQ
N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
  
 
 0.905
nagZ
Beta N-acetyl-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
    
 0.903
GBAG_1533
Chitinase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, chitinase activity, carbohydrate metabolic process and chitin catabolic process; Belongs to the glycosyl hydrolase 18 family.
     
 0.901
lolE
Lipoprotein releasing system transmembrane protein; Protein involved in lipoprotein transporter activity, transport and lipoprotein transport.
      0.853
cobB
SIR2 family NAD-dependent protein deacetylase; Protein involved in NAD+ binding, chromatin silencing, chemotaxis and protein deacetylation; Belongs to the sirtuin family. Class III subfamily.
  
    0.825
GBAG_1091
ROK family N-acetylglucosamine-6P-responsive transcriptional repressor; Protein involved in sequence-specific DNA binding transcription factor activity and regulation of transcription, DNA-templated.
  
     0.765
Your Current Organism:
Buttiauxella agrestis
NCBI taxonomy Id: 1006004
Other names: B. agrestis ATCC 33320, Buttiauxella agrestis ATCC 33320, Buttiauxella agrestis CDC 11786-81, Buttiauxella agrestis CIP 80.31, Buttiauxella agrestis CUETM 77-167, Buttiauxella agrestis DSM 4586, Buttiauxella agrestis str. ATCC 33320, Buttiauxella agrestis strain ATCC 33320
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