STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ydcW4-aminobutyraldehyde dehydrogenase; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (474 aa)    
Predicted Functional Partners:
GabT
Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase; Protein involved in transaminase activity, pyridoxal phosphate binding, 4-aminobutyrate transaminase activity, gamma-aminobutyric acid catabolic process and gamma-aminobutyric acid metabolic process; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.918
GBAG_2206
Hypothetical protein.
   
 
 0.913
ygjG
Putrescine aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
 
 0.913
gltB
Glutamate synthase [NADPH] large chain; Protein involved in glutamate synthase activity, oxidoreductase activity, acting on the CH-NH2 group of donors, oxidoreductase activity, glutamine metabolic process, glutamate biosynthetic process, oxidation-reduction process, metabolic process and nitrogen compound metabolic process.
  
 
 0.882
putA
Transcriptional repressor/proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
 
0.871
GBAG_1976
Periplasmic substrate-binding component of an ABC superfamily spermidine/putrescine transporter; TC:3.A.1.11.1.
 
  
 0.862
GBAG_2213
Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase; Protein involved in transaminase activity, pyridoxal phosphate binding, 4-aminobutyrate transaminase activity, gamma-aminobutyric acid catabolic process and gamma-aminobutyric acid metabolic process; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.836
gdhA
NADP-specific glutamate dehydrogenase; Protein involved in oxidoreductase activity, glutamate biosynthetic process, oxidation-reduction process and cellular amino acid metabolic process; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.825
ydcV
Permease component of an ABC superfamily spermidine/putrescine transporter; TC:3.A.1.11.1; Protein involved in transporter activity and transport.
 
    0.823
GBAG_0237
Glutamate decarboxylase; Protein involved in carboxy-lyase activity, pyridoxal phosphate binding, glutamate decarboxylase activity, glutamate decarboxylation to succinate, carboxylic acid metabolic process and glutamate metabolic process; Belongs to the group II decarboxylase family.
   
 0.818
Your Current Organism:
Buttiauxella agrestis
NCBI taxonomy Id: 1006004
Other names: B. agrestis ATCC 33320, Buttiauxella agrestis ATCC 33320, Buttiauxella agrestis CDC 11786-81, Buttiauxella agrestis CIP 80.31, Buttiauxella agrestis CUETM 77-167, Buttiauxella agrestis DSM 4586, Buttiauxella agrestis str. ATCC 33320, Buttiauxella agrestis strain ATCC 33320
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