node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GBAG_1515 | yfdC | GBAG_1515 | GBAG_2930 | Hypothetical protein. | Protein involved in transporter activity and transport. | 0.447 |
GBAG_1565 | yfdC | GBAG_1565 | GBAG_2930 | Osmotically-inducible lipoprotein E. | Protein involved in transporter activity and transport. | 0.543 |
GBAG_2192 | yfdC | GBAG_2192 | GBAG_2930 | Periplasmic aromatic aldehyde oxidoreductase, FAD binding subunit; Protein involved in oxidoreductase activity, catalytic activity, oxidoreductase activity, acting on CH-OH group of donors, flavin adenine dinucleotide binding and oxidation-reduction process. | Protein involved in transporter activity and transport. | 0.415 |
NirD | cysG | GBAG_1674 | GBAG_3816 | Nitrite reductase [NAD(P)H] large subunit; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding, heme binding, iron-sulfur cluster binding, nitrite reductase [NAD(P)H] activity, NADP binding, 2 iron, 2 sulfur cluster binding, oxidation-reduction process and nitrate assimilation; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.964 |
NirD | yfdC | GBAG_1674 | GBAG_2930 | Nitrite reductase [NAD(P)H] large subunit; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding, heme binding, iron-sulfur cluster binding, nitrite reductase [NAD(P)H] activity, NADP binding, 2 iron, 2 sulfur cluster binding, oxidation-reduction process and nitrate assimilation; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Protein involved in transporter activity and transport. | 0.641 |
can | yfdC | GBAG_0626 | GBAG_2930 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. | Protein involved in transporter activity and transport. | 0.639 |
ccmA | ccmB | GBAG_2929 | GBAG_2928 | ATPase component of an ABC superfamily cytochrome c biogenesis transporter; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Cytochrome c-type biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | 0.999 |
ccmA | ccmC | GBAG_2929 | GBAG_2927 | ATPase component of an ABC superfamily cytochrome c biogenesis transporter; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Cytochrome c-type biogenesis putative heme lyase; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.997 |
ccmA | yfdC | GBAG_2929 | GBAG_2930 | ATPase component of an ABC superfamily cytochrome c biogenesis transporter; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | Protein involved in transporter activity and transport. | 0.524 |
ccmB | ccmA | GBAG_2928 | GBAG_2929 | Cytochrome c-type biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | ATPase component of an ABC superfamily cytochrome c biogenesis transporter; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | 0.999 |
ccmB | ccmC | GBAG_2928 | GBAG_2927 | Cytochrome c-type biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Cytochrome c-type biogenesis putative heme lyase; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.999 |
ccmB | yfdC | GBAG_2928 | GBAG_2930 | Cytochrome c-type biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | Protein involved in transporter activity and transport. | 0.489 |
ccmC | ccmA | GBAG_2927 | GBAG_2929 | Cytochrome c-type biogenesis putative heme lyase; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | ATPase component of an ABC superfamily cytochrome c biogenesis transporter; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. | 0.997 |
ccmC | ccmB | GBAG_2927 | GBAG_2928 | Cytochrome c-type biogenesis putative heme lyase; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | Cytochrome c-type biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | 0.999 |
ccmC | cysG | GBAG_2927 | GBAG_3816 | Cytochrome c-type biogenesis putative heme lyase; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.522 |
ccmC | yfdC | GBAG_2927 | GBAG_2930 | Cytochrome c-type biogenesis putative heme lyase; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | Protein involved in transporter activity and transport. | 0.423 |
cysG | NirD | GBAG_3816 | GBAG_1674 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Nitrite reductase [NAD(P)H] large subunit; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding, heme binding, iron-sulfur cluster binding, nitrite reductase [NAD(P)H] activity, NADP binding, 2 iron, 2 sulfur cluster binding, oxidation-reduction process and nitrate assimilation; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.964 |
cysG | ccmC | GBAG_3816 | GBAG_2927 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Cytochrome c-type biogenesis putative heme lyase; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.522 |
cysG | yfdC | GBAG_3816 | GBAG_2930 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Protein involved in transporter activity and transport. | 0.427 |
yegS | yfdC | GBAG_2691 | GBAG_2930 | Diacylglycerol kinase catalytic domain-containing transcriptional regulator; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily. | Protein involved in transporter activity and transport. | 0.504 |