node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LysC | asd | GBAG_0202 | GBAG_3867 | Aspartokinase; Protein involved in amino acid binding, aspartate kinase activity, lysine biosynthetic process via diaminopimelate, metabolic process and cellular amino acid biosynthetic process; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.962 |
LysC | asnB | GBAG_0202 | GBAG_1088 | Aspartokinase; Protein involved in amino acid binding, aspartate kinase activity, lysine biosynthetic process via diaminopimelate, metabolic process and cellular amino acid biosynthetic process; Belongs to the aspartokinase family. | Protein involved in asparagine synthase (glutamine-hydrolyzing) activity, asparagine biosynthetic process and metabolic process. | 0.905 |
LysC | dapA | GBAG_0202 | GBAG_3022 | Aspartokinase; Protein involved in amino acid binding, aspartate kinase activity, lysine biosynthetic process via diaminopimelate, metabolic process and cellular amino acid biosynthetic process; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.451 |
LysC | metA | GBAG_0202 | GBAG_0111 | Aspartokinase; Protein involved in amino acid binding, aspartate kinase activity, lysine biosynthetic process via diaminopimelate, metabolic process and cellular amino acid biosynthetic process; Belongs to the aspartokinase family. | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | 0.555 |
LysC | metH | GBAG_0202 | GBAG_0118 | Aspartokinase; Protein involved in amino acid binding, aspartate kinase activity, lysine biosynthetic process via diaminopimelate, metabolic process and cellular amino acid biosynthetic process; Belongs to the aspartokinase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.534 |
LysC | metL | GBAG_0202 | GBAG_4289 | Aspartokinase; Protein involved in amino acid binding, aspartate kinase activity, lysine biosynthetic process via diaminopimelate, metabolic process and cellular amino acid biosynthetic process; Belongs to the aspartokinase family. | Aspartokinase/homoserine dehydrogenase; Protein involved in oxidoreductase activity, NADP binding, aspartate kinase activity, oxidation-reduction process, lysine biosynthetic process via diaminopimelate, homoserine biosynthetic process, methionine biosynthetic process, cellular amino acid metabolic process and cellular amino acid biosynthetic process; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.960 |
LysC | thrA | GBAG_0202 | GBAG_3522 | Aspartokinase; Protein involved in amino acid binding, aspartate kinase activity, lysine biosynthetic process via diaminopimelate, metabolic process and cellular amino acid biosynthetic process; Belongs to the aspartokinase family. | Aspartokinase/homoserine dehydrogenase; Protein involved in oxidoreductase activity, NADP binding, aspartate kinase activity, threonine biosynthetic process, oxidation-reduction process, lysine biosynthetic process via diaminopimelate, homoserine biosynthetic process, cellular amino acid metabolic process and cellular amino acid biosynthetic process; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.925 |
LysC | thrB | GBAG_0202 | GBAG_3521 | Aspartokinase; Protein involved in amino acid binding, aspartate kinase activity, lysine biosynthetic process via diaminopimelate, metabolic process and cellular amino acid biosynthetic process; Belongs to the aspartokinase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.841 |
LysC | thrC | GBAG_0202 | GBAG_3520 | Aspartokinase; Protein involved in amino acid binding, aspartate kinase activity, lysine biosynthetic process via diaminopimelate, metabolic process and cellular amino acid biosynthetic process; Belongs to the aspartokinase family. | Protein involved in threonine biosynthetic process. | 0.751 |
asd | LysC | GBAG_3867 | GBAG_0202 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartokinase; Protein involved in amino acid binding, aspartate kinase activity, lysine biosynthetic process via diaminopimelate, metabolic process and cellular amino acid biosynthetic process; Belongs to the aspartokinase family. | 0.962 |
asd | dapA | GBAG_3867 | GBAG_3022 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.939 |
asd | dat | GBAG_3867 | GBAG_1852 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminobutyrate--2-oxoglutarate aminotransferase; Protein involved in transaminase activity, pyridoxal phosphate binding and biosynthetic process; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.909 |
asd | metH | GBAG_3867 | GBAG_0118 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.502 |
asd | metL | GBAG_3867 | GBAG_4289 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartokinase/homoserine dehydrogenase; Protein involved in oxidoreductase activity, NADP binding, aspartate kinase activity, oxidation-reduction process, lysine biosynthetic process via diaminopimelate, homoserine biosynthetic process, methionine biosynthetic process, cellular amino acid metabolic process and cellular amino acid biosynthetic process; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.992 |
asd | thrA | GBAG_3867 | GBAG_3522 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartokinase/homoserine dehydrogenase; Protein involved in oxidoreductase activity, NADP binding, aspartate kinase activity, threonine biosynthetic process, oxidation-reduction process, lysine biosynthetic process via diaminopimelate, homoserine biosynthetic process, cellular amino acid metabolic process and cellular amino acid biosynthetic process; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.963 |
asd | thrB | GBAG_3867 | GBAG_3521 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.577 |
asd | thrC | GBAG_3867 | GBAG_3520 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Protein involved in threonine biosynthetic process. | 0.586 |
asnB | LysC | GBAG_1088 | GBAG_0202 | Protein involved in asparagine synthase (glutamine-hydrolyzing) activity, asparagine biosynthetic process and metabolic process. | Aspartokinase; Protein involved in amino acid binding, aspartate kinase activity, lysine biosynthetic process via diaminopimelate, metabolic process and cellular amino acid biosynthetic process; Belongs to the aspartokinase family. | 0.905 |
asnB | metH | GBAG_1088 | GBAG_0118 | Protein involved in asparagine synthase (glutamine-hydrolyzing) activity, asparagine biosynthetic process and metabolic process. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.477 |
asnB | metL | GBAG_1088 | GBAG_4289 | Protein involved in asparagine synthase (glutamine-hydrolyzing) activity, asparagine biosynthetic process and metabolic process. | Aspartokinase/homoserine dehydrogenase; Protein involved in oxidoreductase activity, NADP binding, aspartate kinase activity, oxidation-reduction process, lysine biosynthetic process via diaminopimelate, homoserine biosynthetic process, methionine biosynthetic process, cellular amino acid metabolic process and cellular amino acid biosynthetic process; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.952 |