STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTL3_0219Alpha-mannosidase; High confidence in function and specificity. (1026 aa)    
Predicted Functional Partners:
DTL3_0217
N-acetyl-beta-glucosaminidase is an exoglucosidase which cleaves N-acetyl-beta-D-galactosamine (NAG) and N-acetyl-beta-D-galactosamine residues from 4-methylumbelliferylated (4MU) substrates, as well as cleaving NAG from chito-oligosaccharides (i.e. NAG polymers); High confidence in function and specificity.
 
  
 0.718
DTL3_0218
Hypothetical protein; Proposed exonuclease-endonuclease-phosphatase domain; High confidence in function and specificity.
 
    0.689
cheY
Chemotaxis protein; Response regulator receiver domain could be identified; High confidence in function and specificity.
  
    0.607
DTL3_0563
Hypothetical protein; Prediceted dehydrogenase; High confidence in function and specificity.
 
    0.509
DTL3_0565
Oxidoreductase family, NAD-binding Rossmann fold protein; High confidence in function and specificity.
 
    0.480
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
   
    0.478
mndA
Beta-mannosidase; Reaction: beta-D-mannoside + H2O -> beta-D-mannose + a non glycosylated sugar acceptor; High confidence in function and specificity; Belongs to the glycosyl hydrolase 2 family.
 
   
 0.471
chiE
Chitobiose ABC transport system, sugar-binding protein; ABC transport systems specific for trehalose/maltose and similar oligosaccharides; High confidence in function and specificity.
 
     0.462
cmk
Cytidylate kinase; It catalyzes the phosphorylation of cytidine 5-monophosphate (dCMP) to cytidine 5 -diphosphate (dCDP) in the presence of ATP or GTP; High confidence in function and specificity.
  
    0.461
nanE
It converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of related sugars that are found as a component of glycoproteins, gangliosides, and other sialoglycoconjugates; High confidence in function and specificity.
 
  
 0.449
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
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