STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTL3_0345ABC-type multidrug transport system, ATPase component; High confidence in function and specificity. (313 aa)    
Predicted Functional Partners:
malK
Maltose-transporting ATPase; Maltose transport system; High confidence in function and specificity; Belongs to the ABC transporter superfamily.
 
    
0.900
DTL3_0924
Putative ABC-2 type transport system permease protein; High confidence in function and specificity.
  
 
 0.842
DTL3_0344
ABC transporter-like protein; High confidence in function and specificity.
 
 
 
0.831
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.791
DTL3_0108
ABC transporter-like protein; High confidence in function and specificity.
0.779
DTL3_0109
ABC transporter-like protein; High confidence in function and specificity.
0.764
pstB
Phosphate import ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
   
0.755
clpB
Chaperone protein ClpB; High confidence in function and specificity; Belongs to the ClpA/ClpB family.
  
  
 0.707
phnK
ABC-type uncharacterized transport system, ATPase component; High confidence in function and specificity.
 
    
0.700
disA
DNA integrity scanning protein DisA; High confidence in function and specificity; Belongs to the DisA family.
       0.678
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
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