STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (329 aa)    
Predicted Functional Partners:
arcA
Arginine deiminase is the first enzyme of the arginine deiminase pathway of arginine degradation; High confidence in function and specificity.
 
 0.999
cpkA
Carbamate kinase works in arginine catabolism and consumes carbamoyl phosphate to convert ADP into ATP; High confidence in function and specificity.
 
 0.998
argG
Argininosuccinate synthase catalyzes the penultimate step in arginine biosynthesis; High confidence in function and specificity; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.995
argH
Argininosuccinate lyase; Arginin biosynthesis; High confidence in function and specificity.
 
  
 0.983
argJ
Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
  
 
 0.982
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
  
 0.956
argD1
Acetylornithine aminotransferase; ArgD is able to catalyze the amination of N-acetyl-L-glutamate 5-semialdehyde to yield N-acetyl-L-ornithine and the amination of N-succinyl-2-amino-6-ketopimelate to yield N-succinyl-L,L-2,6-diaminopimelate; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.913
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.909
argD3
Acetylornithine aminotransferase; An enzyme of arginine biosynthesis; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.875
pyrB
Bifunctional aspartate carbamoyltransferase; The regulatory chain is involved in allosteric regulation of aspartate carbamoyltransferase. The C-terminal metal binding domain has a rubredoxin-like fold and provides the interface with the catalytic chain; High confidence in function and specificity.
   
 0.859
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
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