STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wecB7UDP-N-acetylglucosamine 2-epimerase; This enzyme catalyses the production of UDP-ManNAc from UDP-GlcNAc. Note that some of the enzymes is this family are bifunctional-UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase [5.1.3.23]; Family membership; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (99 aa)    
Predicted Functional Partners:
DTL3_0995
UDP-N-acetylglucosamine 2-epimerase; This enzyme catalyses the production of UDP-ManNAc from UDP-GlcNAc; Hypothetical protein; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
     0.957
DTL3_0994
Glycosyltransferase like family 2; Family membership.
  
  
 0.661
rfbX1
Polysaccharide biosynthesis protein; Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon; High confidence in function and specificity.
 
  
 0.639
wecC1
UDP-N-acetyl-D-mannosamine dehydrogenase; High confidence in function and specificity; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
  
 0.563
wecC3
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Cell envelope biogenesis, outer membrane; High confidence in function and specificity; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
  
 0.563
rfbX3
O-antigen/teichoic acid transporter; High confidence in function and specificity.
 
  
 0.550
rfbB
dTDP-glucose 4,6-dehydratase; dTDP-D-dlucose 4,6,-dehydratase catalyzes the second of four steps in the dTDP-L-rhamnose pathway.In many gram negative bacteria, L-rhamnose is an important constituent of lipopoylsaccharide O-antigen; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.492
DTL3_0998
Group 1 glycosyl transferase; wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide; High confidence in function and specificity.
  
  
 0.485
DTL3_0050
3-amino-5-hydroxybenzoic acid synthase family; High confidence in function and specificity; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.436
DegT
DegT/DnrJ/EryC1/StrS aminotransferase family; High confidence in function and specificity; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.436
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.