STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTL3_1198Methyl-accepting chemotaxis protein; An integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases; Family membership. (97 aa)    
Predicted Functional Partners:
cheA
CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY; High confidence in function and specificity.
  
 
 0.714
DTL3_1044
PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase; PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction; High confidence in function and specificity.
  
 
 0.669
epi
This enzyme converts (2R)-methylmalonyl-CoA to (2S)-methylmalonyl-CoA, which is then a substrate for methylmalonyl-CoA mutase; High confidence in function and specificity.
       0.668
cheW1
Chemotaxis signal transduction protein; A small regulator protein; CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA; High confidence in function and specificity.
  
 
 0.637
cheW3
A small regulator protein. CheW is proposed to form signalling arrays together with CheA and the methyl-accepting chemotaxis proteins (MCPs), which are involved in response modulation; High confidence in function and specificity.
  
 
 0.637
lacI3
Ligand binding domain of the LacI tanscriptional regulator. In most cases, ligands are monosaccharide including lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars; High confidence in function and specificity.
       0.607
DTL3_1197
Methyl-accepting chemotaxis sensory transducer; Cell motility and secretion / Signal transduction mechanisms; High confidence in function and specificity.
      0.487
flgC
Flagellar basal-body rod protein FlgC; FlgC is part of the basal body; High confidence in function and specificity; Belongs to the flagella basal body rod proteins family.
  
 
 0.458
DTL3_0106
Flagellar motor switch protein; High confidence in function and specificity.
  
 
 0.455
flgK
The flagellar hook-associated protein FlgK of bacterial flagella; High confidence in function and specificity; Belongs to the flagella basal body rod proteins family.
  
 
 0.411
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
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