STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTL3_1208Methyl-accepting chemotaxis protein; MCPs are an integral part of the transmembrane protein complex that controls bacterial chemotaxis; High confidence in function and specificity. (774 aa)    
Predicted Functional Partners:
cheA
CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY; High confidence in function and specificity.
 
 0.991
cheR
Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; High confidence in function and specificity.
 
 0.985
cheB
Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.984
cheW3
A small regulator protein. CheW is proposed to form signalling arrays together with CheA and the methyl-accepting chemotaxis proteins (MCPs), which are involved in response modulation; High confidence in function and specificity.
 
 0.982
cheW1
Chemotaxis signal transduction protein; A small regulator protein; CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA; High confidence in function and specificity.
 
 0.981
cheD
Chemoreceptor glutamine deamidase CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  0.972
cheY
Chemotaxis protein; Response regulator receiver domain could be identified; High confidence in function and specificity.
 
  
 0.928
DTL3_1044
PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase; PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction; High confidence in function and specificity.
 
 
 0.751
DTL3_1197
Methyl-accepting chemotaxis sensory transducer; Cell motility and secretion / Signal transduction mechanisms; High confidence in function and specificity.
  
     0.695
DTL3_1323
Methyl-accepting chemotaxis proteins are an integral part of the transmembrane protein complex that controls bacterial chemotaxis; High confidence in function and specificity.
  
     0.688
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
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