STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trkATrkA domain-containing protein; This domain is found in a wide variety of proteins. These protein include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD; High confidence in function and specificity. (141 aa)    
Predicted Functional Partners:
trkG
Potassium uptake protein; TrkG is a potassium ion transporter, closely related to the TrkH potassium ion transporter; High confidence in function and specificity.
 
 
 0.981
trkH
TrkA domain-containing protein; This domain binds to NAD; High confidence in function and specificity.
 
     0.950
hslU
ATP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
  
    0.500
degV
degV family protein; Uncharacterized protein conserved in bacteria., Predicted fatty acid-binding protein; High confidence in function and specificity.
  
     0.438
pyk
Pyruvate kinase; Glycolysis/gluconeogenesis; High confidence in function and specificity; Belongs to the pyruvate kinase family.
       0.435
jag
Putative RNA-binding protein; High confidence in function and specificity.
 
     0.402
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.