STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mreB3MreB is known to be a rod shape-determining protein in bacteria and goes to make up the bacterial cytoskeleton; High confidence in function and specificity. (335 aa)    
Predicted Functional Partners:
DTL3_1581
Cell division protein; Penicillin-binding protein 2; High confidence in function and specificity.
 
 0.947
rodA
Rod shape-determining protein; In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Cell cycle family protein; High confidence in function and specificity; Belongs to the SEDS family.
 
 
 0.790
DTL3_1583
Hypothetical protein; Function unknown; High confidence in function and specificity.
       0.730
ftsW
Cell cycle protein; Bacterial cell division membrane protein [Cell division and chromosome partitioning]; High confidence in function and specificity; Belongs to the SEDS family.
 
 
 0.667
DTL3_1582
Putative membrane protein; Function unknown; Hypothetical protein.
       0.658
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.649
tufB
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
    
 
 0.583
DTL3_1452
Trigger factor is a ribosome-associated molecular chaperone and is the first chaperone to interact with nascent polypeptide; High confidence in function and specificity.
  
   0.557
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.528
minD
Septum site-determining protein MinD; Family membership.
  
 
 0.520
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
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