STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speE1Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (288 aa)    
Predicted Functional Partners:
speD
S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
 
 0.999
DTL3_0575
Ornithine Decarboxylase; High confidence in function and specificity; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.920
DTL3_0188
N-ethylammeline chlorohydrolase; High confidence in function and specificity.
   
  0.910
speE3
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
  
 
0.900
DTL3_1585
XRE family transcriptional regulator; Prokaryotic DNA binding protein belonging to the xenobiotic response element family of transcriptional regulators; High confidence in function and specificity.
       0.779
fliM
Flagellar motor switch protein FliM; High confidence in function and specificity.
   
   0.768
DTL3_0556
Aldo/keto reductase; High confidence in function and specificity.
 
    
 0.495
mreB3
MreB is known to be a rod shape-determining protein in bacteria and goes to make up the bacterial cytoskeleton; High confidence in function and specificity.
  
    0.476
metH
Methionine synthase I (cobalamin-dependent); Amino acid transport and metabolism; High confidence in function and specificity.
     
 0.421
rplD
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
   
    0.412
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.