STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTL3_1747ABC transporter; It is involved in the uptake of various metallic cations such as iron, manganese, and zinc; High confidence in function and specificity. (252 aa)    
Predicted Functional Partners:
DTL3_1746
This family includes periplasmic solute binding proteins such as TroA that interacts with an ATP-binding cassette transport system; High confidence in function and specificity; Belongs to the bacterial solute-binding protein 9 family.
 
 
 0.999
DTL3_1748
Anchored repeat-type ABC transporter, permease subunit; The function of this transporter complex is unknown; High confidence in function and specificity.
 0.999
fur3
This family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes; High confidence in function and specificity; Belongs to the Fur family.
  
  
 0.882
troR
Mn-dependent transcriptional regulator; High confidence in function and specificity.
  
  
 0.579
dppA11
Peptidase M55 D-aminopeptidase; It is a binuclear zinc-dependent, D-specific aminopeptidase; High confidence in function and specificity.
       0.516
fur1
Ferric uptake regulator and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism; Family membership; Belongs to the Fur family.
  
  
 0.500
DTL3_1749
Predicted sugar phosphatases of the HAD superfamily; High confidence in function and specificity; Belongs to the HAD-like hydrolase superfamily.
       0.474
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
       0.438
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
 
 
 
 0.433
ecfA1
Energy-coupling factor transporter ATP-binding protein; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems; High confidence in function and specificity.
 
  
0.416
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
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