STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTL3_1879The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, all of which use a nucleophilic aspartate in their phosphoryl transfer reaction; High confidence in function and specificity. (196 aa)    
Predicted Functional Partners:
DTL3_0887
Phosphoglucomutase; Alpha-D-glucose 1-phosphate <=> alpha-D-glucose 6-phosphate; High confidence in function and specificity.
  
 
 0.909
pgcA
Phosphoglucomutase; Second step of UDP-GlcNAc biosynthesis; High confidence in function and specificity.
  
 
 0.909
glk
Glucokinase; Kinase (ROK) family regulators that are characterized by carbohydrate-sensing domains shared with sugar kinases; High confidence in function and specificity.
   
 
  0.904
galM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
   
 
  0.903
glgP
Phosphorylases, and homologs believed to use inorganic phosphate to cleave an alpha 1,4 linkage between the terminal glucose residue and the rest of the polymer (maltodextrin, glycogen, etc.); High confidence in function and specificity.
  
 
 0.829
DTL3_0297
Glucose-1-phosphate adenylyltransferase, GlgC subunit; High confidence in function and specificity.
  
 
 0.809
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
  
 
 0.809
DTL3_0329
The glycosyltransferase family 36 includes cellobiose phosphorylase, cellodextrin phosphorylase, chitobiose phosphorylase; High confidence in function and specificity.
    
  0.801
pulA
Pullulanase; Enzymes that cleave alpha-1,6 linkages in pullulan and release maltotriose are called pullulanases although pullulan itself may not be the natural substrate; High confidence in function and specificity; Belongs to the glycosyl hydrolase 13 family.
    
  0.801
DTL3_1183
Cellobiose phosphorylase; It catalyzes the reversible phosphorolysis of cellobionic acid; High confidence in function and specificity.
    
  0.801
Your Current Organism:
Defluviitoga tunisiensis
NCBI taxonomy Id: 1006576
Other names: D. tunisiensis, DSM 23805, Defluviitoga tunisiensis Ben Hania et al. 2012, JCM 17210, Thermotogaceae bacterium SulfLac1, strain SulfLac1
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