STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glyASerine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate. (409 aa)    
Predicted Functional Partners:
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 0.977
lpd
Dihydrolipoyl dehydrogenase.
  
 0.950
thyA
Thymidylate synthase; ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived.
  
 
 0.946
fmt
methionyl-tRNA formyltransferase.
    
 0.933
rpiB
Ribose 5-phosphate isomerase.
 
    0.928
pepA
Peptidase M17.
  
 
 0.832
nadD
Nicotinate-nucleotide adenylyltransferase.
     
 0.796
GCW_03475
Nicotinate phosphoribosyltransferase.
   
 
 0.787
ffh
With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins.
  
  
 0.785
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
  
 0.764
Your Current Organism:
Mycoplasma gallisepticum
NCBI taxonomy Id: 1006581
Other names: M. gallisepticum S6, Mycoplasma gallisepticum S6, Mycoplasma gallisepticum str. S6, Mycoplasma gallisepticum strain S6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.