STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PT7_0429Alpha-ketoglutarate decarboxylase. (956 aa)    
Predicted Functional Partners:
PT7_0430
Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.999
PT7_1018
Dihydrolipoamide dehydrogenase.
 
 0.999
PT7_0431
Dihydrolipoamide dehydrogenase.
 
 0.992
PT7_0839
Dihydrolipoamide dehydrogenase.
  
 0.983
PT7_1009
Mercuric ion reductase.
  
 0.980
PT7_2789
Dihydrolipoamide dehydrogenase.
  
 0.980
PT7_1922
Isocitrate dehydrogenase.
  
 
 0.973
sucC
Succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
 0.972
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 
 0.950
PT7_3438
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 0.947
Your Current Organism:
Pusillimonas sp. T77
NCBI taxonomy Id: 1007105
Other names: P. sp. T7-7, Pusillimonas sp. T7-7
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