BN1708_012084 protein (Verticillium longisporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

Coexpression

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[Homology]

Score

BN1708_012084

AA_TRNA_LIGASE_II domain-containing protein. (669 aa)

Predicted Functional Partners:

BN1708_001050

0.923

BN1708_017190

0.915

BN1708_000399

0.915

BN1708_015897

0.915

BN1708_008203

0.905

BN1708_008200

0.905

BN1708_000043

0.903

BN1708_016287

0.903

BN1708_019476

0.903

BN1708_002540

0.873

Your Current Organism:

Verticillium longisporum

NCBI taxonomy Id: 100787
Other names: CBS 124.64, CBS H-19247, MUCL 9802, NRRL 54793, PD687, V. longisporum, Verticillium dahliae var. longisporum, Verticillium longisporum (C. Stark) Karapapa et al.

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... protein annotations:

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BN1708_000043	BN1708_001050	A0A0G4KCG2	A0A0G4MGJ4	S1 motif domain-containing protein.	Uncharacterized protein.	0.903
BN1708_000043	BN1708_002540	A0A0G4KCG2	A0A0G4KTP2	S1 motif domain-containing protein.	PRA-CH domain-containing protein.	0.434
BN1708_000043	BN1708_012084	A0A0G4KCG2	A0A0G4L6C7	S1 motif domain-containing protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.903
BN1708_000399	BN1708_001050	A0A0G4LCV4	A0A0G4MGJ4	Uncharacterized protein.	Uncharacterized protein.	0.915
BN1708_000399	BN1708_002540	A0A0G4LCV4	A0A0G4KTP2	Uncharacterized protein.	PRA-CH domain-containing protein.	0.997
BN1708_000399	BN1708_008200	A0A0G4LCV4	A0A0G4N277	Uncharacterized protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.449
BN1708_000399	BN1708_008203	A0A0G4LCV4	A0A0G4N1S3	Uncharacterized protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.449
BN1708_000399	BN1708_012084	A0A0G4LCV4	A0A0G4L6C7	Uncharacterized protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.915
BN1708_001050	BN1708_000043	A0A0G4MGJ4	A0A0G4KCG2	Uncharacterized protein.	S1 motif domain-containing protein.	0.903
BN1708_001050	BN1708_000399	A0A0G4MGJ4	A0A0G4LCV4	Uncharacterized protein.	Uncharacterized protein.	0.915
BN1708_001050	BN1708_002540	A0A0G4MGJ4	A0A0G4KTP2	Uncharacterized protein.	PRA-CH domain-containing protein.	0.873
BN1708_001050	BN1708_008200	A0A0G4MGJ4	A0A0G4N277	Uncharacterized protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.905
BN1708_001050	BN1708_008203	A0A0G4MGJ4	A0A0G4N1S3	Uncharacterized protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.905
BN1708_001050	BN1708_012084	A0A0G4MGJ4	A0A0G4L6C7	Uncharacterized protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.923
BN1708_001050	BN1708_015897	A0A0G4MGJ4	A0A0G4M9X9	Uncharacterized protein.	Uncharacterized protein.	0.915
BN1708_001050	BN1708_016287	A0A0G4MGJ4	A0A0G4MIM5	Uncharacterized protein.	S1 motif domain-containing protein.	0.903
BN1708_001050	BN1708_017190	A0A0G4MGJ4	A0A0G4KVX0	Uncharacterized protein.	HisG_C domain-containing protein.	0.915
BN1708_001050	BN1708_019476	A0A0G4MGJ4	A0A0G4MJ26	Uncharacterized protein.	S1 motif domain-containing protein.	0.903
BN1708_002540	BN1708_000043	A0A0G4KTP2	A0A0G4KCG2	PRA-CH domain-containing protein.	S1 motif domain-containing protein.	0.434
BN1708_002540	BN1708_000399	A0A0G4KTP2	A0A0G4LCV4	PRA-CH domain-containing protein.	Uncharacterized protein.	0.997

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.805

expected number of edges:

10

PPI enrichment p-value:

2.67e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008608

Attachment of spindle microtubules to kinetochore

8 of 22

2.27

5.87

1.24e-13

GO:0007059

Chromosome segregation

9 of 119

1.59

3.02

1.05e-10

GO:0051301

Cell division

9 of 121

1.58

3.0

1.05e-10

GO:0022402

Cell cycle process

10 of 295

1.24

1.85

1.43e-09

GO:0007052

Mitotic spindle organization

3 of 22

1.84

1.16

0.0051

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051010

Microtubule plus-end binding

6 of 10

2.49

5.16

5.56e-11

GO:0015631

Tubulin binding

8 of 49

1.92

4.25

1.42e-11

GO:0043015

Gamma-tubulin binding

2 of 6

2.23

0.9

0.0217

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042729

DASH complex

9 of 10

2.66

9.17

2.51e-19

GO:0005819

Spindle

10 of 42

2.09

6.59

5.06e-18

GO:0005874

Microtubule

10 of 50

2.01

6.08

1.81e-17

GO:0072686

Mitotic spindle

7 of 18

2.3

5.83

2.45e-13

GO:0005876

Spindle microtubule

2 of 11

1.97

1.05

0.0096

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5880

DASH complex

6 of 6

2.71

5.88

5.04e-12

CL:5857

Kinetochore

7 of 18

2.3

5.33

4.62e-12

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0042729

DASH complex

8 of 8

2.71

8.16

7.57e-17

GOCC:0099080

Supramolecular complex

9 of 99

1.67

3.58

1.98e-12

GOCC:0005876

Spindle microtubule

3 of 8

2.28

4.11e-05

GOCC:0005819

Spindle

4 of 28

1.86

2.19

1.71e-05

GOCC:0015630

Microtubule cytoskeleton

5 of 78

1.52

1.8

1.71e-05

(more ...)

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