BN1708_012543 protein (Verticillium longisporum)

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Predicted Interactions

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Score

BN1708_012543

Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (1128 aa)

Predicted Functional Partners:

BN1708_012866

0.980

BN1708_007177

0.980

BN1708_007180

0.980

BN1708_004405

0.959

BN1708_005328

0.959

BN1708_015871

0.955

BN1708_015874

0.955

BN1708_019435

0.955

BN1708_007071

0.955

PSD2

0.954

Your Current Organism:

Verticillium longisporum

NCBI taxonomy Id: 100787
Other names: CBS 124.64, CBS H-19247, MUCL 9802, NRRL 54793, PD687, V. longisporum, Verticillium dahliae var. longisporum, Verticillium longisporum (C. Stark) Karapapa et al.

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BN1708_004405	BN1708_007071	A0A0G4M0Z9	A0A0G4MQL6	Uncharacterized protein.	Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.	0.934
BN1708_004405	BN1708_007177	A0A0G4M0Z9	A0A0G4MR88	Uncharacterized protein.	Uncharacterized protein.	0.544
BN1708_004405	BN1708_007180	A0A0G4M0Z9	A0A0G4MRM7	Uncharacterized protein.	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.544
BN1708_004405	BN1708_012543	A0A0G4M0Z9	A0A0G4LAU7	Uncharacterized protein.	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family.	0.959
BN1708_004405	BN1708_012866	A0A0G4M0Z9	A0A0G4LFI8	Uncharacterized protein.	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.544
BN1708_004405	BN1708_015871	A0A0G4M0Z9	A0A0G4M9E8	Uncharacterized protein.	Uncharacterized protein.	0.943
BN1708_004405	BN1708_015874	A0A0G4M0Z9	A0A0G4MAE5	Uncharacterized protein.	Uncharacterized protein.	0.943
BN1708_004405	BN1708_019435	A0A0G4M0Z9	A0A0G4MJA8	Uncharacterized protein.	Uncharacterized protein.	0.934
BN1708_004405	PSD2	A0A0G4M0Z9	A0A0G4KZX8	Uncharacterized protein.	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.	0.986
BN1708_005328	BN1708_007071	A0A0G4MA19	A0A0G4MQL6	Uncharacterized protein.	Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.	0.934
BN1708_005328	BN1708_007177	A0A0G4MA19	A0A0G4MR88	Uncharacterized protein.	Uncharacterized protein.	0.544
BN1708_005328	BN1708_007180	A0A0G4MA19	A0A0G4MRM7	Uncharacterized protein.	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.544
BN1708_005328	BN1708_012543	A0A0G4MA19	A0A0G4LAU7	Uncharacterized protein.	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family.	0.959
BN1708_005328	BN1708_012866	A0A0G4MA19	A0A0G4LFI8	Uncharacterized protein.	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.544
BN1708_005328	BN1708_015871	A0A0G4MA19	A0A0G4M9E8	Uncharacterized protein.	Uncharacterized protein.	0.943
BN1708_005328	BN1708_015874	A0A0G4MA19	A0A0G4MAE5	Uncharacterized protein.	Uncharacterized protein.	0.943
BN1708_005328	BN1708_019435	A0A0G4MA19	A0A0G4MJA8	Uncharacterized protein.	Uncharacterized protein.	0.934
BN1708_005328	PSD2	A0A0G4MA19	A0A0G4KZX8	Uncharacterized protein.	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.	0.986
BN1708_007071	BN1708_004405	A0A0G4MQL6	A0A0G4M0Z9	Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.	Uncharacterized protein.	0.934
BN1708_007071	BN1708_005328	A0A0G4MQL6	A0A0G4MA19	Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.	Uncharacterized protein.	0.934

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

42

average node degree:

7.64

avg. local clustering coefficient:

0.917

expected number of edges:

14

PPI enrichment p-value:

2.05e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019344

Cysteine biosynthetic process

5 of 7

2.29

3.85

1.62e-08

GO:1901607

Alpha-amino acid biosynthetic process

11 of 81

1.57

3.51

1.12e-14

GO:0009097

Isoleucine biosynthetic process

4 of 7

2.2

2.9

1.46e-06

GO:0009069

Serine family amino acid metabolic process

6 of 29

1.76

2.86

5.38e-08

GO:0009099

Valine biosynthetic process

3 of 4

2.32

2.25

4.84e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004795

Threonine synthase activity

3 of 3

2.44

2.06

0.00014

GO:0016835

Carbon-oxygen lyase activity

5 of 41

1.53

1.63

8.00e-05

GO:0016829

Lyase activity

7 of 104

1.27

1.47

1.22e-05

GO:0030170

Pyridoxal phosphate binding

4 of 30

1.57

1.43

0.00048

GO:0052656

L-isoleucine transaminase activity

2 of 2

2.44

1.24

0.0052

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 876

0.5

0.38

0.0038

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1781

Sulfur amino acid biosynthetic process, and Threonine metabolic process

6 of 21

1.9

3.27

1.80e-08

CL:1719

Cellular amino acid biosynthetic process

8 of 52

1.63

3.0

6.62e-10

CL:1811

Threonine synthase activity, and Threonine biosynthetic process

3 of 5

2.22

1.89

0.00023

CL:1500

Biosynthesis of amino acids, and Carbon metabolism

11 of 187

1.21

1.87

4.02e-11

CL:1549

Valine, leucine and isoleucine biosynthesis

3 of 12

1.84

1.38

0.0016

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01230

Biosynthesis of amino acids

11 of 130

1.37

2.55

1.57e-13

map00260

Glycine, serine and threonine metabolism

6 of 46

1.56

2.29

2.93e-07

map00750

Vitamin B6 metabolism

3 of 10

1.92

1.84

0.00016

map00290

Valine, leucine and isoleucine biosynthesis

4 of 27

1.61

1.73

7.59e-05

map00270

Cysteine and methionine metabolism

4 of 36

1.49

1.51

0.00016

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0663

Pyridoxal phosphate

3 of 17

1.69

1.2

0.0030

KW-0028

Amino-acid biosynthesis

4 of 45

1.39

1.07

0.0027

KW-0822

Tryptophan biosynthesis

2 of 6

1.96

0.99

0.0126

KW-0456

Lyase

4 of 59

1.27

0.98

0.0030

KW-0032

Aminotransferase

2 of 16

1.54

0.67

0.0448

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00291

Pyridoxal-phosphate dependent enzyme

5 of 11

2.1

3.06

3.88e-07

PF01063

Amino-transferase class IV

2 of 2

2.44

0.99

0.0151

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036052

Tryptophan synthase beta chain-like, PALP domain superfamily

5 of 11

2.1

2.89

1.01e-06

IPR001926

Tryptophan synthase beta chain-like, PALP domain

5 of 11

2.1

2.89

1.01e-06

IPR000634

Serine/threonine dehydratase, pyridoxal-phosphate-binding site

3 of 3

2.44

1.92

0.00026

IPR043132

Branched-chain-amino-acid aminotransferase-like, C-terminal

2 of 2

2.44

0.93

0.0197

IPR043131

Branched-chain-amino-acid aminotransferase-like, N-terminal

2 of 2

2.44

0.93

0.0197

(more ...)

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