BN1708_013463 protein (Verticillium longisporum)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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Score

BN1708_013463

Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (531 aa)

Predicted Functional Partners:

BN1708_002636

0.988

BN1708_002469

0.986

BN1708_002479

0.986

BN1708_000131

0.982

BN1708_013234

0.981

BN1708_000798

0.981

BN1708_006294

0.981

BN1708_008535

0.976

BN1708_008550

0.976

BN1708_009722

0.971

Your Current Organism:

Verticillium longisporum

NCBI taxonomy Id: 100787
Other names: CBS 124.64, CBS H-19247, MUCL 9802, NRRL 54793, PD687, V. longisporum, Verticillium dahliae var. longisporum, Verticillium longisporum (C. Stark) Karapapa et al.

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BN1708_000131	BN1708_000798	A0A0G4LKN1	A0A0G4M7L7	Histone H2A; Belongs to the histone H2A family.	Uncharacterized protein.	0.878
BN1708_000131	BN1708_002469	A0A0G4LKN1	A0A0G4KTN7	Histone H2A; Belongs to the histone H2A family.	Uncharacterized protein.	0.884
BN1708_000131	BN1708_002479	A0A0G4LKN1	A0A0G4M1M1	Histone H2A; Belongs to the histone H2A family.	Uncharacterized protein.	0.884
BN1708_000131	BN1708_002636	A0A0G4LKN1	A0A0G4KX76	Histone H2A; Belongs to the histone H2A family.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.987
BN1708_000131	BN1708_006294	A0A0G4LKN1	A0A0G4MIR4	Histone H2A; Belongs to the histone H2A family.	Uncharacterized protein.	0.673
BN1708_000131	BN1708_008535	A0A0G4LKN1	A0A0G4N5G0	Histone H2A; Belongs to the histone H2A family.	Chromatin modification-related protein.	0.871
BN1708_000131	BN1708_008550	A0A0G4LKN1	A0A0G4N5I3	Histone H2A; Belongs to the histone H2A family.	Chromatin modification-related protein.	0.871
BN1708_000131	BN1708_009722	A0A0G4LKN1	A0A0G4KK35	Histone H2A; Belongs to the histone H2A family.	MRG domain-containing protein.	0.403
BN1708_000131	BN1708_013234	A0A0G4LKN1	A0A0G4LIJ0	Histone H2A; Belongs to the histone H2A family.	Uncharacterized protein.	0.673
BN1708_000131	BN1708_013463	A0A0G4LKN1	A0A0G4LLY8	Histone H2A; Belongs to the histone H2A family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.982
BN1708_000798	BN1708_000131	A0A0G4M7L7	A0A0G4LKN1	Uncharacterized protein.	Histone H2A; Belongs to the histone H2A family.	0.878
BN1708_000798	BN1708_002469	A0A0G4M7L7	A0A0G4KTN7	Uncharacterized protein.	Uncharacterized protein.	0.988
BN1708_000798	BN1708_002479	A0A0G4M7L7	A0A0G4M1M1	Uncharacterized protein.	Uncharacterized protein.	0.988
BN1708_000798	BN1708_002636	A0A0G4M7L7	A0A0G4KX76	Uncharacterized protein.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.792
BN1708_000798	BN1708_008535	A0A0G4M7L7	A0A0G4N5G0	Uncharacterized protein.	Chromatin modification-related protein.	0.958
BN1708_000798	BN1708_008550	A0A0G4M7L7	A0A0G4N5I3	Uncharacterized protein.	Chromatin modification-related protein.	0.958
BN1708_000798	BN1708_009722	A0A0G4M7L7	A0A0G4KK35	Uncharacterized protein.	MRG domain-containing protein.	0.967
BN1708_000798	BN1708_013463	A0A0G4M7L7	A0A0G4LLY8	Uncharacterized protein.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.981
BN1708_002469	BN1708_000131	A0A0G4KTN7	A0A0G4LKN1	Uncharacterized protein.	Histone H2A; Belongs to the histone H2A family.	0.884
BN1708_002469	BN1708_000798	A0A0G4KTN7	A0A0G4M7L7	Uncharacterized protein.	Uncharacterized protein.	0.988

page 1 of 5

Network Stats

number of nodes:

9

number of edges:

15

average node degree:

3.33

avg. local clustering coefficient:

0.917

expected number of edges:

16

PPI enrichment p-value:

0.675

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006479

Protein methylation

6 of 57

1.9

2.91

2.29e-07

GO:0016571

Histone methylation

4 of 25

2.08

2.31

2.22e-05

GO:0006325

Chromatin organization

7 of 177

1.48

2.04

8.15e-07

GO:0051568

Histone H3-K4 methylation

3 of 11

2.31

1.91

0.00024

GO:0016570

Histone modification

5 of 88

1.63

1.88

2.97e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030527

Structural constituent of chromatin

3 of 9

2.4

1.75

0.00055

GO:0046982

Protein heterodimerization activity

3 of 29

1.89

1.13

0.0061

GO:0042800

Histone methyltransferase activity (H3-K4 specific)

2 of 5

2.48

0.98

0.0162

GO:0005515

Protein binding

6 of 689

0.82

0.48

0.0311

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0035097

Histone methyltransferase complex

4 of 9

2.53

3.22

7.64e-07

GO:0048188

Set1C/COMPASS complex

3 of 8

2.45

2.34

3.90e-05

GO:0000786

Nucleosome

3 of 11

2.31

2.18

6.80e-05

GO:0005694

Chromosome

8 of 326

1.27

1.64

7.64e-07

GO:0070210

Rpd3L-Expanded complex

2 of 3

2.7

1.62

0.0011

(more ...)

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:34202282

(2021) Using Genealogical Concordance and Coalescent-Based Species Delimitation to Assess Species Boundaries in the Diaporthe eres Complex.

2 of 2

2.88

1.82

0.00049

PMID:25264384

(2014) Species limits in Diaporthe: molecular re-assessment of D. citri, D. cytosporella, D. foeniculina and D. rudis.

2 of 2

2.88

1.82

0.00049

PMID:34456375

(2020) Mating genes in Calonectria and evidence for a heterothallic ancestral state.

2 of 3

2.7

1.81

0.00049

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2696

Histone methyltransferase complex, and Structural constituent of chromatin

8 of 25

2.38

6.92

1.24e-15

CL:2689

PKMTs methylate histone lysines, and Structural constituent of chromatin

9 of 37

2.26

6.86

1.78e-16

CL:2475

Mixed, incl. Histone modification, and Chromatin remodeling

10 of 171

1.65

3.75

3.88e-14

CL:2726

Set1C/COMPASS complex, and Histone H3

4 of 10

2.48

3.49

1.97e-07

CL:2699

Mixed, incl. Nucleosome core, and Regulation of PTEN gene transcription

4 of 13

2.37

3.26

4.33e-07

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00310

Lysine degradation

3 of 82

1.44

0.76

0.0240

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-3214841

PKMTs methylate histone lysines

5 of 29

2.11

3.1

3.48e-07

MAP-4839726

Chromatin organization

6 of 81

1.75

2.62

3.48e-07

MAP-3247509

Chromatin modifying enzymes

6 of 81

1.75

2.62

3.48e-07

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000786

Nucleosome

3 of 12

2.28

1.66

0.00072

GOCC:0035097

Histone methyltransferase complex

3 of 14

2.21

1.65

0.00072

GOCC:0070210

Rpd3L-Expanded complex

2 of 5

2.48

1.31

0.0039

GOCC:0000785

Chromatin

5 of 145

1.42

1.26

0.00072

GOCC:0048188

Set1C/COMPASS complex

2 of 7

2.33

1.2

0.0060

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0158

Chromosome

3 of 10

2.36

2.07

0.00012

KW-0544

Nucleosome core

2 of 5

2.48

1.4

0.0026

KW-0539

Nucleus

6 of 309

1.17

1.16

0.00013

KW-0853

WD repeat

3 of 99

1.36

0.79

0.0164

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR007125

Histone H2A/H2B/H3

3 of 6

2.58

1.85

0.00038

IPR000164

Histone H3/CENP-A

2 of 2

2.88

1.15

0.0083

IPR009072

Histone-fold

3 of 25

1.96

1.11

0.0073

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00428

Histone H3

2 of 3

2.7

1.27

0.0049

SM00317

SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain

2 of 14

2.03

0.82

0.0292

SM00320

WD40 repeats

3 of 113

1.3

0.63

0.0415

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