BN1708_014636 protein (Verticillium longisporum)

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query proteins and first shell of interactors

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second shell of interactors

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

Coexpression

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[Homology]

Score

BN1708_014636

ACB domain-containing protein. (242 aa)

Predicted Functional Partners:

BN1708_002131

0.857

BN1708_014449

0.854

BN1708_005532

0.782

BN1708_020731

0.780

BN1708_014517

0.772

BN1708_019097

0.772

BN1708_009971

0.763

BN1708_011243

0.763

BN1708_011489

0.763

BN1708_003447

0.763

Your Current Organism:

Verticillium longisporum

NCBI taxonomy Id: 100787
Other names: CBS 124.64, CBS H-19247, MUCL 9802, NRRL 54793, PD687, V. longisporum, Verticillium dahliae var. longisporum, Verticillium longisporum (C. Stark) Karapapa et al.

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BN1708_002131	BN1708_003447	A0A0G4KHR9	A0A0G4LHB0	Pex2_Pex12 domain-containing protein.	SH3 domain-containing protein.	0.995
BN1708_002131	BN1708_005532	A0A0G4KHR9	A0A0G4MCR2	Pex2_Pex12 domain-containing protein.	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.886
BN1708_002131	BN1708_009971	A0A0G4KHR9	A0A0G4KMH4	Pex2_Pex12 domain-containing protein.	SH3 domain-containing protein.	0.995
BN1708_002131	BN1708_011243	A0A0G4KHR9	A0A0G4KYE7	Pex2_Pex12 domain-containing protein.	Mitochondrial fission 1 protein; Has a role in mitochondrial fission.	0.934
BN1708_002131	BN1708_011489	A0A0G4KHR9	A0A0G4L0U6	Pex2_Pex12 domain-containing protein.	RING-type domain-containing protein.	0.934
BN1708_002131	BN1708_014449	A0A0G4KHR9	A0A0G4LWC4	Pex2_Pex12 domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.987
BN1708_002131	BN1708_014517	A0A0G4KHR9	A0A0G4LWD0	Pex2_Pex12 domain-containing protein.	Peroxisomal membrane protein PEX16.	0.913
BN1708_002131	BN1708_014636	A0A0G4KHR9	A0A0G4LYQ8	Pex2_Pex12 domain-containing protein.	ACB domain-containing protein.	0.857
BN1708_002131	BN1708_019097	A0A0G4KHR9	A0A0G4MET3	Pex2_Pex12 domain-containing protein.	Peroxisomal membrane protein PEX16.	0.913
BN1708_002131	BN1708_020731	A0A0G4KHR9	A0A0G4KRP7	Pex2_Pex12 domain-containing protein.	Uncharacterized protein.	0.980
BN1708_003447	BN1708_002131	A0A0G4LHB0	A0A0G4KHR9	SH3 domain-containing protein.	Pex2_Pex12 domain-containing protein.	0.995
BN1708_003447	BN1708_005532	A0A0G4LHB0	A0A0G4MCR2	SH3 domain-containing protein.	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.841
BN1708_003447	BN1708_011243	A0A0G4LHB0	A0A0G4KYE7	SH3 domain-containing protein.	Mitochondrial fission 1 protein; Has a role in mitochondrial fission.	0.856
BN1708_003447	BN1708_011489	A0A0G4LHB0	A0A0G4L0U6	SH3 domain-containing protein.	RING-type domain-containing protein.	0.856
BN1708_003447	BN1708_014449	A0A0G4LHB0	A0A0G4LWC4	SH3 domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.923
BN1708_003447	BN1708_014517	A0A0G4LHB0	A0A0G4LWD0	SH3 domain-containing protein.	Peroxisomal membrane protein PEX16.	0.829
BN1708_003447	BN1708_014636	A0A0G4LHB0	A0A0G4LYQ8	SH3 domain-containing protein.	ACB domain-containing protein.	0.763
BN1708_003447	BN1708_019097	A0A0G4LHB0	A0A0G4MET3	SH3 domain-containing protein.	Peroxisomal membrane protein PEX16.	0.829
BN1708_003447	BN1708_020731	A0A0G4LHB0	A0A0G4KRP7	SH3 domain-containing protein.	Uncharacterized protein.	0.909
BN1708_005532	BN1708_002131	A0A0G4MCR2	A0A0G4KHR9	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family.	Pex2_Pex12 domain-containing protein.	0.886

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Network Stats

number of nodes:

11

number of edges:

19

average node degree:

3.45

avg. local clustering coefficient:

0.827

expected number of edges:

12

PPI enrichment p-value:

0.028

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043648

Dicarboxylic acid metabolic process

6 of 44

1.7

2.35

1.50e-06

GO:0009089

Lysine biosynthetic process via diaminopimelate

4 of 12

2.09

2.22

3.46e-05

GO:0019877

Diaminopimelate biosynthetic process

3 of 8

2.14

1.73

0.00046

GO:0044281

Small molecule metabolic process

8 of 739

0.6

0.4

0.0164

GO:0008152

Metabolic process

11 of 1964

0.31

0.25

0.0322

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1373

0.43

0.31

0.0186

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:927

Lysine biosynthesis, and Aspartate kinase activity

7 of 14

2.26

5.14

9.63e-12

CL:930

Monobactam biosynthesis

4 of 5

2.47

3.18

8.31e-07

CL:1329

Mixed, incl. Pantothenate biosynthetic process, and Helix-hairpin-helix motif

4 of 13

2.05

2.43

1.03e-05

CL:1333

Pantothenate biosynthetic process, and Biotin-protein ligase activity

3 of 6

2.26

2.01

0.00014

CL:945

Aminotransferases, class-I, pyridoxal-phosphate-binding site, and Diaminopimelate biosynthesis

2 of 5

2.17

1.02

0.0126

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00300

Lysine biosynthesis

7 of 34

1.88

3.78

2.52e-10

map00261

Monobactam biosynthesis

4 of 8

2.26

3.05

8.96e-07

map01230

Biosynthesis of amino acids

7 of 194

1.12

1.26

7.68e-06

map01120

Microbial metabolism in diverse environments

6 of 349

0.8

0.59

0.0043

map01110

Biosynthesis of secondary metabolites

7 of 549

0.67

0.5

0.0044

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0457

Lysine biosynthesis

6 of 8

2.44

5.13

4.82e-11

KW-0220

Diaminopimelate biosynthesis

5 of 6

2.49

4.4

2.50e-09

KW-0456

Lyase

4 of 67

1.34

1.12

0.0014

KW-0704

Schiff base

2 of 9

1.91

0.94

0.0157

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01130

Dihydrodipicolinate synthetase family

2 of 2

2.57

1.23

0.0057

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