BN1708_005830 protein (Verticillium longisporum)

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second shell of interactors

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Known Interactions

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Predicted Interactions

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gene fusions

gene co-occurrence

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BN1708_005830

Hydrolase_4 domain-containing protein. (403 aa)

Predicted Functional Partners:

BN1708_009397

0.741

BN1708_014926

0.741

BN1708_015707

0.741

BN1708_007024

0.741

BN1708_013314

0.740

BN1708_015340

0.585

BN1708_016437

0.579

BN1708_002636

0.565

BN1708_020344

0.565

BN1708_017495

0.563

Your Current Organism:

Verticillium longisporum

NCBI taxonomy Id: 100787
Other names: CBS 124.64, CBS H-19247, MUCL 9802, NRRL 54793, PD687, V. longisporum, Verticillium dahliae var. longisporum, Verticillium longisporum (C. Stark) Karapapa et al.

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BN1708_002636	BN1708_005830	A0A0G4KX76	A0A0G4ME47	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Hydrolase_4 domain-containing protein.	0.565
BN1708_005830	BN1708_002636	A0A0G4ME47	A0A0G4KX76	Hydrolase_4 domain-containing protein.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.565
BN1708_005830	BN1708_007024	A0A0G4ME47	A0A0G4MQJ4	Hydrolase_4 domain-containing protein.	Uncharacterized protein.	0.741
BN1708_005830	BN1708_009397	A0A0G4ME47	A0A0G4KGF2	Hydrolase_4 domain-containing protein.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.741
BN1708_005830	BN1708_013314	A0A0G4ME47	A0A0G4LJP5	Hydrolase_4 domain-containing protein.	Uncharacterized protein.	0.740
BN1708_005830	BN1708_014926	A0A0G4ME47	A0A0G4M0B5	Hydrolase_4 domain-containing protein.	Uncharacterized protein.	0.741
BN1708_005830	BN1708_015340	A0A0G4ME47	A0A0G4M3K6	Hydrolase_4 domain-containing protein.	Uncharacterized protein.	0.585
BN1708_005830	BN1708_015707	A0A0G4ME47	A0A0G4M7K7	Hydrolase_4 domain-containing protein.	Uncharacterized protein.	0.741
BN1708_005830	BN1708_016437	A0A0G4ME47	A0A0G4MLX8	Hydrolase_4 domain-containing protein.	YTH domain-containing protein.	0.579
BN1708_005830	BN1708_017495	A0A0G4ME47	A0A0G4L324	Hydrolase_4 domain-containing protein.	Uncharacterized protein.	0.563
BN1708_005830	BN1708_020344	A0A0G4ME47	A0A0G4MU33	Hydrolase_4 domain-containing protein.	Uncharacterized protein.	0.565
BN1708_007024	BN1708_005830	A0A0G4MQJ4	A0A0G4ME47	Uncharacterized protein.	Hydrolase_4 domain-containing protein.	0.741
BN1708_007024	BN1708_009397	A0A0G4MQJ4	A0A0G4KGF2	Uncharacterized protein.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.982
BN1708_007024	BN1708_013314	A0A0G4MQJ4	A0A0G4LJP5	Uncharacterized protein.	Uncharacterized protein.	0.981
BN1708_007024	BN1708_014926	A0A0G4MQJ4	A0A0G4M0B5	Uncharacterized protein.	Uncharacterized protein.	0.981
BN1708_007024	BN1708_015707	A0A0G4MQJ4	A0A0G4M7K7	Uncharacterized protein.	Uncharacterized protein.	0.981
BN1708_009397	BN1708_005830	A0A0G4KGF2	A0A0G4ME47	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	Hydrolase_4 domain-containing protein.	0.741
BN1708_009397	BN1708_007024	A0A0G4KGF2	A0A0G4MQJ4	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	Uncharacterized protein.	0.982
BN1708_009397	BN1708_013314	A0A0G4KGF2	A0A0G4LJP5	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	Uncharacterized protein.	0.981
BN1708_009397	BN1708_014926	A0A0G4KGF2	A0A0G4M0B5	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	Uncharacterized protein.	0.982

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.842

expected number of edges:

36

PPI enrichment p-value:

0.942

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044571

[2Fe-2S] cluster assembly

3 of 3

2.79

2.33

5.32e-05

GO:0009069

Serine family amino acid metabolic process

4 of 36

1.83

1.78

0.00017

GO:0006790

Sulfur compound metabolic process

6 of 137

1.43

1.57

5.32e-05

GO:0006534

Cysteine metabolic process

3 of 20

1.96

1.45

0.0014

GO:0001514

Selenocysteine incorporation

2 of 2

2.79

1.38

0.0031

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031071

Cysteine desulfurase activity

3 of 7

2.42

1.86

0.00033

GO:0051537

2 iron, 2 sulfur cluster binding

3 of 33

1.74

1.14

0.0048

GO:0030170

Pyridoxal phosphate binding

3 of 54

1.53

0.92

0.0111

GO:0051536

Iron-sulfur cluster binding

4 of 132

1.27

0.85

0.0081

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1790

0.53

0.42

0.0024

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3110

Mixed, incl. Sulfur relay system, and Iron-sulfur cluster assembly

9 of 70

1.9

4.63

2.05e-13

CL:3112

Mixed, incl. Sulfur relay system, and Iron-sulfur cluster assembly

6 of 39

1.97

3.49

1.02e-08

CL:3116

[2Fe-2S] cluster assembly, and tRNA thio-modification

3 of 6

2.48

2.24

6.48e-05

CL:3231

Mixed, incl. Selenocysteine metabolic process, and Protein carrier chaperone

3 of 7

2.42

2.18

7.93e-05

CL:3157

Iron-sulfur cluster assembly, and Cysteine desulfurase, SufS

3 of 13

2.15

1.82

0.00029

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

hoh00450

Selenocompound metabolism

6 of 16

2.36

5.1

3.15e-11

hoh00730

Thiamine metabolism

3 of 14

2.12

1.98

0.00013

hoh04122

Sulfur relay system

3 of 18

2.01

1.89

0.00016

hoh01100

Metabolic pathways

8 of 778

0.8

0.71

0.00016

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990229

Iron-sulfur cluster assembly complex

3 of 5

2.56

2.27

6.00e-05

GOCC:0005759

Mitochondrial matrix

3 of 11

2.22

1.94

0.00019

GOCC:0005654

Nucleoplasm

3 of 23

1.9

1.51

0.00091

GOCC:0005622

Intracellular

9 of 2009

0.44

0.31

0.0188

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0663

Pyridoxal phosphate

7 of 60

1.85

3.64

4.90e-10

KW-0711

Selenium

2 of 4

2.48

1.4

0.0026

KW-0808

Transferase

8 of 865

0.75

0.61

0.00097

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00155

Aminotransferase class I and II

3 of 13

2.15

1.49

0.0014

PF00266

Aminotransferase class-V

3 of 15

2.09

1.48

0.0014

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR016454

Cysteine desulfurase

6 of 6

2.79

5.88

6.67e-12

IPR000192

Aminotransferase class V domain

6 of 13

2.45

5.0

9.75e-11

IPR015424

Pyridoxal phosphate-dependent transferase

7 of 56

1.88

3.63

9.65e-10

IPR015421

Pyridoxal phosphate-dependent transferase, major domain

7 of 56

1.88

3.63

9.65e-10

IPR015422

Pyridoxal phosphate-dependent transferase, small domain

6 of 50

1.87

3.08

4.56e-08

(more ...)

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