BN1708_006655 protein (Verticillium longisporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

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Databases

Textmining

[Homology]

Score

BN1708_006655

Uncharacterized protein. (712 aa)

Predicted Functional Partners:

BN1708_009478

0.540

BN1708_016508

0.540

BN1708_001777

0.540

BN1708_016926

0.540

BN1708_008758

0.540

BN1708_011304

0.502

BN1708_012824

0.493

BN1708_000716

0.477

BN1708_006752

0.476

BN1708_001020

0.452

Your Current Organism:

Verticillium longisporum

NCBI taxonomy Id: 100787
Other names: CBS 124.64, CBS H-19247, MUCL 9802, NRRL 54793, PD687, V. longisporum, Verticillium dahliae var. longisporum, Verticillium longisporum (C. Stark) Karapapa et al.

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structured XML interaction data, according to the 'PSI-MI' data standard

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BN1708_000716	BN1708_006655	A0A0G4LZD7	A0A0G4MLU9	Uncharacterized protein.	Uncharacterized protein.	0.477
BN1708_000716	BN1708_011304	A0A0G4LZD7	A0A0G4KS11	Uncharacterized protein.	Uncharacterized protein.	0.449
BN1708_000716	BN1708_012824	A0A0G4LZD7	A0A0G4LF93	Uncharacterized protein.	Uncharacterized protein.	0.433
BN1708_001020	BN1708_006655	A0A0G4MGH0	A0A0G4MLU9	Uncharacterized protein.	Uncharacterized protein.	0.452
BN1708_001777	BN1708_006655	A0A0G4N540	A0A0G4MLU9	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	Uncharacterized protein.	0.540
BN1708_006655	BN1708_000716	A0A0G4MLU9	A0A0G4LZD7	Uncharacterized protein.	Uncharacterized protein.	0.477
BN1708_006655	BN1708_001020	A0A0G4MLU9	A0A0G4MGH0	Uncharacterized protein.	Uncharacterized protein.	0.452
BN1708_006655	BN1708_001777	A0A0G4MLU9	A0A0G4N540	Uncharacterized protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.540
BN1708_006655	BN1708_006752	A0A0G4MLU9	A0A0G4MMC4	Uncharacterized protein.	Uncharacterized protein.	0.476
BN1708_006655	BN1708_008758	A0A0G4MLU9	A0A0G4N846	Uncharacterized protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.540
BN1708_006655	BN1708_009478	A0A0G4MLU9	A0A0G4KHR3	Uncharacterized protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.540
BN1708_006655	BN1708_011304	A0A0G4MLU9	A0A0G4KS11	Uncharacterized protein.	Uncharacterized protein.	0.502
BN1708_006655	BN1708_012824	A0A0G4MLU9	A0A0G4LF93	Uncharacterized protein.	Uncharacterized protein.	0.493
BN1708_006655	BN1708_016508	A0A0G4MLU9	A0A0G4MPB6	Uncharacterized protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.540
BN1708_006655	BN1708_016926	A0A0G4MLU9	A0A0G4N7W4	Uncharacterized protein.	Uncharacterized protein.	0.540
BN1708_006752	BN1708_006655	A0A0G4MMC4	A0A0G4MLU9	Uncharacterized protein.	Uncharacterized protein.	0.476
BN1708_006752	BN1708_011304	A0A0G4MMC4	A0A0G4KS11	Uncharacterized protein.	Uncharacterized protein.	0.447
BN1708_006752	BN1708_012824	A0A0G4MMC4	A0A0G4LF93	Uncharacterized protein.	Uncharacterized protein.	0.429
BN1708_008758	BN1708_006655	A0A0G4N846	A0A0G4MLU9	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	Uncharacterized protein.	0.540
BN1708_009478	BN1708_006655	A0A0G4KHR3	A0A0G4MLU9	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	Uncharacterized protein.	0.540

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

30

average node degree:

5.45

avg. local clustering coefficient:

0.844

expected number of edges:

19

PPI enrichment p-value:

0.00899

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008202

Steroid metabolic process

3 of 19

2.06

1.22

0.0046

GO:0006629

Lipid metabolic process

5 of 315

1.06

0.6

0.0294

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016491

Oxidoreductase activity

7 of 681

0.88

0.62

0.0070

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2434

Short-chain dehydrogenase/reductase SDR

6 of 14

2.5

5.23

4.17e-11

CL:2172

Mixed, incl. ACP-like superfamily, and Fatty acid biosynthetic process

9 of 151

1.64

3.26

3.65e-11

CL:2225

Polyketide synthase dehydratase, and Ketoacyl-synthetase C-terminal extension

3 of 6

2.56

2.23

7.02e-05

CL:2437

Short-chain dehydrogenase/reductase, conserved site, and Biotin metabolism

2 of 6

2.39

1.17

0.0070

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

10 of 1725

0.63

0.51

0.00070

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF08659

KR domain

6 of 62

1.85

2.92

1.22e-07

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR002347

Short-chain dehydrogenase/reductase SDR

7 of 64

1.9

3.56

2.28e-09

IPR036291

NAD(P)-binding domain superfamily

8 of 214

1.44

2.17

5.26e-08

IPR020904

Short-chain dehydrogenase/reductase, conserved site

4 of 32

1.96

1.98

8.37e-05

IPR040097

Fatty acyl-AMP ligase /fatty acyl-CoA ligase

2 of 8

2.26

0.74

0.0438

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