STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMYC01_200002Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (300 aa)    
Predicted Functional Partners:
MMYC01_205847
Transcription initiation factor IIE subunit alpha.
   
 0.999
MMYC01_201187
Putative DNA repair helicase ercc3.
    
 0.995
MMYC01_209847
DNA repair helicase rad15.
    
 0.993
MMYC01_208994
Serine/threonine-protein kinase KIN28; Belongs to the protein kinase superfamily.
   
 0.993
MMYC01_205419
General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.
   
 0.993
MMYC01_200734
RNA polymerase II transcription factor B subunit 4.
    
 0.993
MMYC01_207268
Cyclin CCL1; Belongs to the cyclin family.
    
 0.991
MMYC01_204788
RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.991
MMYC01_206499
Transcription initiation factor IIF subunit beta.
   
 0.986
MMYC01_203622
Transcription initiation factor IIF subunit alpha.
   
 0.985
Your Current Organism:
Madurella mycetomatis
NCBI taxonomy Id: 100816
Other names: M. mycetomatis, Madurella ikedae, Madurella mycetomi, Streptotrix mycetomatis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.