STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMYC01_200012BRCT-containing protein 1. (844 aa)    
Predicted Functional Partners:
MMYC01_205758
DNA repair protein crb2.
    
 0.981
MMYC01_202450
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
   
 0.976
MMYC01_201073
S-M checkpoint control protein rad4.
   
 
 0.957
MMYC01_204959
Structural maintenance of chromosomes protein 6.
   
 
 0.956
MMYC01_203576
Set1 complex component ash2.
    
 0.939
MMYC01_209930
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
    
 0.918
MMYC01_207310
Histone H2A; Belongs to the histone H2A family.
    
 0.917
MMYC01_208352
ATP-dependent DNA helicase srs2.
   
 
 0.917
MMYC01_202816
Cx9C motif-containing protein 4, mitochondrial.
    
 0.917
MMYC01_204132
Set1 complex component swd1.
   
 0.908
Your Current Organism:
Madurella mycetomatis
NCBI taxonomy Id: 100816
Other names: M. mycetomatis, Madurella ikedae, Madurella mycetomi, Streptotrix mycetomatis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.