STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMYC01_2076633-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate. (292 aa)    
Predicted Functional Partners:
MMYC01_208066
Pantothenate synthetase.
 
 0.999
MMYC01_209154
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.859
MMYC01_205524
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.859
MMYC01_201714
Putative branched-chain-amino-acid aminotransferase TOXF.
    
 0.859
MMYC01_207191
Putative dehydratase IlvD1.
     
 0.854
MMYC01_201742
Putative dihydroxy-acid dehydratase, mitochondrial.
     
 0.854
MMYC01_200388
Putative dihydroxy-acid dehydratase, mitochondrial.
     
 0.854
MMYC01_200843
Putative 2-dehydropantoate 2-reductase.
     
 0.840
MMYC01_200090
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
     
 0.811
MMYC01_205680
Putative 2-dehydropantoate 2-reductase.
     
 0.741
Your Current Organism:
Madurella mycetomatis
NCBI taxonomy Id: 100816
Other names: M. mycetomatis, Madurella ikedae, Madurella mycetomi, Streptotrix mycetomatis
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