node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MMYC01_200507 | MMYC01_202268 | A0A175WH13 | A0A175W873 | Nuclear protein localization protein 4. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.868 |
MMYC01_200507 | MMYC01_202344 | A0A175WH13 | A0A175WDY5 | Nuclear protein localization protein 4. | Crossover junction endonuclease MUS81. | 0.964 |
MMYC01_200507 | MMYC01_202747 | A0A175WH13 | A0A175WF63 | Nuclear protein localization protein 4. | Mating-type switching protein swi10. | 0.971 |
MMYC01_200507 | MMYC01_206175 | A0A175WH13 | A0A175VZ88 | Nuclear protein localization protein 4. | Ubiquitin-conjugating enzyme E2 4; Belongs to the ubiquitin-conjugating enzyme family. | 0.913 |
MMYC01_200507 | MMYC01_207688 | A0A175WH13 | A0A175VX50 | Nuclear protein localization protein 4. | Nuclear transport factor 2. | 0.962 |
MMYC01_200507 | MMYC01_207689 | A0A175WH13 | A0A175VWA0 | Nuclear protein localization protein 4. | Golgi apparatus membrane protein TVP18. | 0.873 |
MMYC01_200507 | MMYC01_209558 | A0A175WH13 | A0A175VRB7 | Nuclear protein localization protein 4. | Uncharacterized protein. | 0.895 |
MMYC01_200507 | MMYC01_210584 | A0A175WH13 | A0A175VN17 | Nuclear protein localization protein 4. | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | 0.895 |
MMYC01_202268 | MMYC01_200507 | A0A175W873 | A0A175WH13 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Nuclear protein localization protein 4. | 0.868 |
MMYC01_202268 | MMYC01_202344 | A0A175W873 | A0A175WDY5 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Crossover junction endonuclease MUS81. | 0.964 |
MMYC01_202268 | MMYC01_202747 | A0A175W873 | A0A175WF63 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Mating-type switching protein swi10. | 0.517 |
MMYC01_202268 | MMYC01_202965 | A0A175W873 | A0A175WDP8 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.989 |
MMYC01_202268 | MMYC01_207688 | A0A175W873 | A0A175VX50 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Nuclear transport factor 2. | 0.889 |
MMYC01_202268 | MMYC01_207689 | A0A175W873 | A0A175VWA0 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Golgi apparatus membrane protein TVP18. | 0.542 |
MMYC01_202344 | MMYC01_200507 | A0A175WDY5 | A0A175WH13 | Crossover junction endonuclease MUS81. | Nuclear protein localization protein 4. | 0.964 |
MMYC01_202344 | MMYC01_202268 | A0A175WDY5 | A0A175W873 | Crossover junction endonuclease MUS81. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.964 |
MMYC01_202344 | MMYC01_202747 | A0A175WDY5 | A0A175WF63 | Crossover junction endonuclease MUS81. | Mating-type switching protein swi10. | 0.999 |
MMYC01_202344 | MMYC01_202965 | A0A175WDY5 | A0A175WDP8 | Crossover junction endonuclease MUS81. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.981 |
MMYC01_202344 | MMYC01_206175 | A0A175WDY5 | A0A175VZ88 | Crossover junction endonuclease MUS81. | Ubiquitin-conjugating enzyme E2 4; Belongs to the ubiquitin-conjugating enzyme family. | 0.611 |
MMYC01_202344 | MMYC01_207688 | A0A175WDY5 | A0A175VX50 | Crossover junction endonuclease MUS81. | Nuclear transport factor 2. | 0.873 |