STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMYC01_205372NADP-dependent malic enzyme. (778 aa)    
Predicted Functional Partners:
MMYC01_202948
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.903
MMYC01_208762
Malate dehydrogenase.
  
 0.887
MMYC01_200579
Malate dehydrogenase.
  
 0.887
MMYC01_209979
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.883
MMYC01_201181
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.877
MMYC01_209728
Acetolactate synthase.
  
 
 0.868
MMYC01_206913
Citrate synthase; Belongs to the citrate synthase family.
  
 0.865
MMYC01_206858
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 
 0.865
MMYC01_201305
Citrate synthase; Belongs to the citrate synthase family.
  
 0.865
MMYC01_201401
Acetolactate synthase small subunit, mitochondrial.
   
 
 0.846
Your Current Organism:
Madurella mycetomatis
NCBI taxonomy Id: 100816
Other names: M. mycetomatis, Madurella ikedae, Madurella mycetomi, Streptotrix mycetomatis
Server load: low (26%) [HD]