node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | MMYC01_200100 | A0A175W4Q3 | A0A150ASS4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | MMYC01_200308 | A0A175W4Q3 | A0A175WE06 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | MMYC01_203635 | A0A175W4Q3 | A0A175W538 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | MMYC01_204575 | A0A175W4Q3 | A0A175W509 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | MMYC01_204855 | A0A175W4Q3 | A0A175W5W3 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cell division control protein 45. | 0.998 |
MCM7 | MMYC01_205893 | A0A175W4Q3 | A0A175VWT2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.997 |
MCM7 | MMYC01_206604 | A0A175W4Q3 | A0A175VVZ4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 2. | 0.996 |
MCM7 | MMYC01_207643 | A0A175W4Q3 | A0A175VWJ7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cell division control protein; Belongs to the CDC6/cdc18 family. | 0.998 |
MCM7 | MMYC01_207679 | A0A175W4Q3 | A0A175W183 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 6. | 0.916 |
MCM7 | MMYC01_208960 | A0A175W4Q3 | A0A175VRL5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 4. | 0.990 |
MMYC01_200100 | MCM7 | A0A150ASS4 | A0A175W4Q3 | DNA helicase; Belongs to the MCM family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
MMYC01_200100 | MMYC01_200308 | A0A150ASS4 | A0A175WE06 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
MMYC01_200100 | MMYC01_203635 | A0A150ASS4 | A0A175W538 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
MMYC01_200100 | MMYC01_204575 | A0A150ASS4 | A0A175W509 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
MMYC01_200100 | MMYC01_204855 | A0A150ASS4 | A0A175W5W3 | DNA helicase; Belongs to the MCM family. | Cell division control protein 45. | 0.998 |
MMYC01_200100 | MMYC01_205893 | A0A150ASS4 | A0A175VWT2 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.997 |
MMYC01_200100 | MMYC01_206604 | A0A150ASS4 | A0A175VVZ4 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 2. | 0.998 |
MMYC01_200100 | MMYC01_207643 | A0A150ASS4 | A0A175VWJ7 | DNA helicase; Belongs to the MCM family. | Cell division control protein; Belongs to the CDC6/cdc18 family. | 0.998 |
MMYC01_200100 | MMYC01_207679 | A0A150ASS4 | A0A175W183 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 6. | 0.920 |
MMYC01_200100 | MMYC01_208960 | A0A150ASS4 | A0A175VRL5 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 4. | 0.991 |