node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
E7G8F0_9FIRM | E7GE45_9FIRM | GCA_000269565_02884 | GCA_000269565_02508 | Diacylglycerol kinase. | DAGKc domain-containing protein. | 0.819 |
E7G8F0_9FIRM | groL | GCA_000269565_02884 | GCA_000269565_00044 | Diacylglycerol kinase. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.932 |
E7GC73_9FIRM | clpP | GCA_000269565_00016 | GCA_000269565_01138 | Pyruvate-flavodoxin oxidoreductase. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.889 |
E7GC73_9FIRM | dnaK | GCA_000269565_00016 | GCA_000269565_00116 | Pyruvate-flavodoxin oxidoreductase. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.642 |
E7GC73_9FIRM | dnaK-2 | GCA_000269565_00016 | GCA_000269565_00507 | Pyruvate-flavodoxin oxidoreductase. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.642 |
E7GC73_9FIRM | groL | GCA_000269565_00016 | GCA_000269565_00044 | Pyruvate-flavodoxin oxidoreductase. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.930 |
E7GC73_9FIRM | grpE | GCA_000269565_00016 | GCA_000269565_00508 | Pyruvate-flavodoxin oxidoreductase. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.762 |
E7GC73_9FIRM | htpG | GCA_000269565_00016 | GCA_000269565_00413 | Pyruvate-flavodoxin oxidoreductase. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.597 |
E7GC73_9FIRM | sigA | GCA_000269565_00016 | GCA_000269565_01004 | Pyruvate-flavodoxin oxidoreductase. | RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.425 |
E7GE45_9FIRM | E7G8F0_9FIRM | GCA_000269565_02508 | GCA_000269565_02884 | DAGKc domain-containing protein. | Diacylglycerol kinase. | 0.819 |
E7GE45_9FIRM | groL | GCA_000269565_02508 | GCA_000269565_00044 | DAGKc domain-containing protein. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.932 |
clpP | E7GC73_9FIRM | GCA_000269565_01138 | GCA_000269565_00016 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Pyruvate-flavodoxin oxidoreductase. | 0.889 |
clpP | dnaK | GCA_000269565_01138 | GCA_000269565_00116 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.674 |
clpP | dnaK-2 | GCA_000269565_01138 | GCA_000269565_00507 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.674 |
clpP | groL | GCA_000269565_01138 | GCA_000269565_00044 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.869 |
clpP | groS | GCA_000269565_01138 | GCA_000269565_00045 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.910 |
clpP | grpE | GCA_000269565_01138 | GCA_000269565_00508 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.834 |
clpP | htpG | GCA_000269565_01138 | GCA_000269565_00413 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.677 |
clpP | sigA | GCA_000269565_01138 | GCA_000269565_01004 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.583 |
dnaK | E7GC73_9FIRM | GCA_000269565_00116 | GCA_000269565_00016 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Pyruvate-flavodoxin oxidoreductase. | 0.642 |