STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E7GB40_9FIRMProphage Lp1 protein 65. (234 aa)    
Predicted Functional Partners:
E7GB39_9FIRM
Uncharacterized protein.
       0.791
sigA
RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.762
E7GE42_9FIRM
Cold-shock domain-containing protein.
      0.717
E7GCA4_9FIRM
Uncharacterized protein.
  
  
 0.602
E7GE73_9FIRM
Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.588
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.501
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.500
E7GDL7_9FIRM
Lactamase_B domain-containing protein.
     
 0.498
E7G9M6_9FIRM
Competence/damage inducible protein cinA.
     
 0.467
E7GAE1_9FIRM
Competence/damage inducible protein; Belongs to the CinA family.
     
 0.467
Your Current Organism:
Coprobacillus cateniformis
NCBI taxonomy Id: 100884
Other names: C. cateniformis, CIP 106690, Coprobacillus catenaformis, Coprobacillus cateniformis corrig. Kageyama and Benno 2000, Coprobacillus sp. 29_1, Coprobacillus sp. D6, JCM 10604, strain RCA1-24
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