STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Irak3Interleukin-1 receptor-associated kinase 3 isoform X1. (609 aa)    
Predicted Functional Partners:
Irak2
Interleukin-1 receptor-associated kinase-like 2.
    
0.987
Irak4
Interleukin-1 receptor-associated kinase 4.
    
0.984
Traf6
TNF receptor-associated factor 6.
   
 0.974
Irak1
Interleukin 1 receptor associated kinase 1.
  
 
0.929
Ngfr
Tumor necrosis factor receptor superfamily member 16.
    
 0.926
Myd88
Myeloid differentiation primary response protein MyD88.
   
 0.857
Tollip
Toll-interacting protein isoform X1.
   
 0.761
Tlr4
Toll-like receptor 4.
   
 0.639
Tlr2
Toll-like receptor 2.
   
 0.635
Socs1
Suppressor of cytokine signaling 1.
   
 0.629
Your Current Organism:
Mus caroli
NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.