STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ptk2Protein tyrosine kinase 2. (1091 aa)    
Predicted Functional Partners:
Grb2
Growth factor receptor-binding protein 2.
   
 0.997
Bcar1
Breast cancer anti-estrogen resistance protein 1 isoform X1.
    
 0.996
Src
Proto-oncogene tyrosine-protein kinase Src.
   
0.994
Sos1
Son of sevenless homolog 1.
    
 0.989
Dcc
Deleted in colorectal carcinoma.
   
 0.989
Pxn
Paxillin isoform X1.
    
 0.988
Mef2c
Myocyte-specific enhancer factor 2C isoform X1.
   
 
 0.982
Egfr
Epidermal growth factor receptor.
    
0.979
Fyn
Tyrosine-protein kinase Fyn isoform X1.
   
0.974
Ptpn11
Tyrosine-protein phosphatase non-receptor type 11 isoform X1.
   
 0.960
Your Current Organism:
Mus caroli
NCBI taxonomy Id: 10089
Other names: M. caroli, Mus formosanus, Ryukyu mouse, ricefield mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.