STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SeboxHomeobox protein SEBOX; Probable transcription factor involved in the control of specification of mesoderm and endoderm; Belongs to the paired homeobox family. (190 aa)    
Predicted Functional Partners:
Omt2b
Oocyte maturation, beta.
   
  
 0.639
Car8
Carbonic anhydrase-related protein; Does not have a carbonic anhydrase catalytic activity; Belongs to the alpha-carbonic anhydrase family.
   
  
 0.556
Tmem200a
Transmembrane protein 200A.
      
 0.538
Zfp959
Zinc finger protein 959.
   
 
 0.534
Scgn
Secretagogin.
    
 
 0.505
H1f8
Histone H1oo; May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
   
  
 0.503
Ooep
Oocyte-expressed protein homolog; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.
      
 0.480
Skint10
Selection and upkeep of intraepithelial T-cells protein 10; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus; Belongs to the SKINT family.
      
 0.457
Obox1
Oocyte-specific homeobox 1.
   
  
 0.451
Cabp5
Calcium-binding protein 5; Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. Involved in the transmission of light signals. May positively regulate neurotransmitter vesicle endocytosis and exocytosis in a salt-dependent manner. May play a role in the extension and network organization of neurites.
   
 
 0.440
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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