node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bysl | Fau | ENSMUSP00000024783 | ENSMUSP00000136358 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 0.982 |
Bysl | Ltv1 | ENSMUSP00000024783 | ENSMUSP00000019950 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. | Protein LTV1 homolog; Belongs to the LTV1 family. | 0.999 |
Bysl | Nob1 | ENSMUSP00000024783 | ENSMUSP00000003946 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. | RNA-binding protein NOB1; May play a role in mRNA degradation (By similarity). Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity). | 0.999 |
Bysl | Pno1 | ENSMUSP00000024783 | ENSMUSP00000020317 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. | RNA-binding protein PNO1; Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA. Belongs to the PNO1 family. | 0.985 |
Bysl | Riok1 | ENSMUSP00000024783 | ENSMUSP00000021866 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. | Serine/threonine-protein kinase RIO1; Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor (By similarity). The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit (By similarity). Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity). The catalytic activity regulates its [...] | 0.904 |
Bysl | Riok2 | ENSMUSP00000024783 | ENSMUSP00000024620 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. | Serine/threonine-protein kinase RIO2; Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre- rRNA to the mature 18S rRNA. May regulate the timing of the metaphase- anaphase transition during mitotic progression, and its phosphorylation, may regulate this function. | 0.997 |
Bysl | Rps3a1 | ENSMUSP00000024783 | ENSMUSP00000029722 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. | 40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. | 0.980 |
Bysl | Rps5 | ENSMUSP00000024783 | ENSMUSP00000104179 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. | 40S ribosomal protein S5, N-terminally processed; Belongs to the universal ribosomal protein uS7 family. | 0.984 |
Bysl | Rpsa | ENSMUSP00000024783 | ENSMUSP00000035105 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] | 0.931 |
Bysl | Tsr1 | ENSMUSP00000024783 | ENSMUSP00000039027 | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. | Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus. | 0.999 |
Fau | Bysl | ENSMUSP00000136358 | ENSMUSP00000024783 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits; Belongs to the bystin family. | 0.982 |
Fau | Ltv1 | ENSMUSP00000136358 | ENSMUSP00000019950 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | Protein LTV1 homolog; Belongs to the LTV1 family. | 0.979 |
Fau | Nob1 | ENSMUSP00000136358 | ENSMUSP00000003946 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | RNA-binding protein NOB1; May play a role in mRNA degradation (By similarity). Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity). | 0.979 |
Fau | Pno1 | ENSMUSP00000136358 | ENSMUSP00000020317 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | RNA-binding protein PNO1; Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA. Belongs to the PNO1 family. | 0.979 |
Fau | Riok1 | ENSMUSP00000136358 | ENSMUSP00000021866 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | Serine/threonine-protein kinase RIO1; Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor (By similarity). The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit (By similarity). Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity). The catalytic activity regulates its [...] | 0.979 |
Fau | Riok2 | ENSMUSP00000136358 | ENSMUSP00000024620 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | Serine/threonine-protein kinase RIO2; Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre- rRNA to the mature 18S rRNA. May regulate the timing of the metaphase- anaphase transition during mitotic progression, and its phosphorylation, may regulate this function. | 0.979 |
Fau | Rps3a1 | ENSMUSP00000136358 | ENSMUSP00000029722 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. | 0.999 |
Fau | Rps5 | ENSMUSP00000136358 | ENSMUSP00000104179 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 40S ribosomal protein S5, N-terminally processed; Belongs to the universal ribosomal protein uS7 family. | 0.999 |
Fau | Rpsa | ENSMUSP00000136358 | ENSMUSP00000035105 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] | 0.999 |
Fau | Tsr1 | ENSMUSP00000136358 | ENSMUSP00000039027 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus. | 0.979 |