node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Amdhd2 | Carhsp1 | ENSMUSP00000036141 | ENSMUSP00000008537 | N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway; Belongs to the metallo-dependent hydrolases superfamily. NagA family. | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | 0.492 |
Carhsp1 | Amdhd2 | ENSMUSP00000008537 | ENSMUSP00000036141 | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway; Belongs to the metallo-dependent hydrolases superfamily. NagA family. | 0.492 |
Carhsp1 | Cops7a | ENSMUSP00000008537 | ENSMUSP00000108058 | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | COP9 signalosome complex subunit 7a; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF- type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-de [...] | 0.534 |
Carhsp1 | Gm14698 | ENSMUSP00000008537 | ENSMUSP00000094153 | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | Serine/threonine/tyrosine-interacting protein; Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2) (By similarity). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2) (By similarity). By binding to the F-box of FBXW7, prevents the assembly of FBXW7 into the SCF E3 ubiquitin-protein ligase complex, and thereby inhibits degradation of its substrates (By similarity). Plays a role in spermatogenesis. Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. | 0.641 |
Carhsp1 | Pdxdc1 | ENSMUSP00000008537 | ENSMUSP00000023361 | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | Pyridoxal-dependent decarboxylase domain-containing protein 1; Belongs to the group II decarboxylase family. | 0.472 |
Carhsp1 | Pnpo | ENSMUSP00000008537 | ENSMUSP00000018803 | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | Pyridoxine-5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.523 |
Carhsp1 | Rps11 | ENSMUSP00000008537 | ENSMUSP00000003521 | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | 40S ribosomal protein S11. | 0.467 |
Carhsp1 | Rps23 | ENSMUSP00000008537 | ENSMUSP00000054490 | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | 40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.456 |
Carhsp1 | Samd4b | ENSMUSP00000008537 | ENSMUSP00000147037 | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | Protein Smaug homolog 2; Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A (By similarity); Belongs to the SMAUG family. | 0.581 |
Carhsp1 | Slc38a7 | ENSMUSP00000008537 | ENSMUSP00000037023 | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | Putative sodium-coupled neutral amino acid transporter 7; Mediates sodium-dependent transport of amino acids. Substrate preference is ranked l-glutamine > l-histidine > l-serine > l-alanine > l-asparagine > l-aspartic acid > l-glutamic acid > l-methionine > l- leucine > l-glycine. | 0.480 |
Carhsp1 | Styx | ENSMUSP00000008537 | ENSMUSP00000153854 | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | Serine/threonine/tyrosine interaction protein. | 0.521 |
Cops7a | Carhsp1 | ENSMUSP00000108058 | ENSMUSP00000008537 | COP9 signalosome complex subunit 7a; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF- type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-de [...] | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | 0.534 |
Cops7a | Slc38a7 | ENSMUSP00000108058 | ENSMUSP00000037023 | COP9 signalosome complex subunit 7a; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF- type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-de [...] | Putative sodium-coupled neutral amino acid transporter 7; Mediates sodium-dependent transport of amino acids. Substrate preference is ranked l-glutamine > l-histidine > l-serine > l-alanine > l-asparagine > l-aspartic acid > l-glutamic acid > l-methionine > l- leucine > l-glycine. | 0.553 |
Gm14698 | Carhsp1 | ENSMUSP00000094153 | ENSMUSP00000008537 | Serine/threonine/tyrosine-interacting protein; Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2) (By similarity). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2) (By similarity). By binding to the F-box of FBXW7, prevents the assembly of FBXW7 into the SCF E3 ubiquitin-protein ligase complex, and thereby inhibits degradation of its substrates (By similarity). Plays a role in spermatogenesis. Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | 0.641 |
Pdxdc1 | Carhsp1 | ENSMUSP00000023361 | ENSMUSP00000008537 | Pyridoxal-dependent decarboxylase domain-containing protein 1; Belongs to the group II decarboxylase family. | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | 0.472 |
Pnpo | Carhsp1 | ENSMUSP00000018803 | ENSMUSP00000008537 | Pyridoxine-5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | 0.523 |
Pnpo | Slc38a7 | ENSMUSP00000018803 | ENSMUSP00000037023 | Pyridoxine-5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative sodium-coupled neutral amino acid transporter 7; Mediates sodium-dependent transport of amino acids. Substrate preference is ranked l-glutamine > l-histidine > l-serine > l-alanine > l-asparagine > l-aspartic acid > l-glutamic acid > l-methionine > l- leucine > l-glycine. | 0.536 |
Rps11 | Carhsp1 | ENSMUSP00000003521 | ENSMUSP00000008537 | 40S ribosomal protein S11. | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | 0.467 |
Rps11 | Rps23 | ENSMUSP00000003521 | ENSMUSP00000054490 | 40S ribosomal protein S11. | 40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.999 |
Rps23 | Carhsp1 | ENSMUSP00000054490 | ENSMUSP00000008537 | 40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | Calcium-regulated heat stable protein 1; Binds mRNA and regulates the stability of target mRNA. | 0.456 |